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John

Great product, original Japanese Lactis EL027826792JP
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Mike

Good effect. I shall order again. Original made-in-japan package as promised EG401137451JP
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May

Real Japanese laennec. Thank you! I shall order again. EJ377189782JP
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Bob

Great effect! Got my hair back in 3 months. EG401137588JP
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Nike

Lost 3 kilos since started to drink it last month. Great for fitness EG299855913JP
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Any

Bought it for my son. Good effect and great service. EG299855961JP
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Nya

Original touchi, fast delivery and good price. Thank you. EG401137156JP
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Sam

Good medicine. Think it really helps me to fight cancer. EL025661542JP
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John

3 times cheaper than in our country! And great effect for knees EJ365886698JP
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Mike

Great thing to support diet. Lost 4 kilos for 6 weeks. Shall order more EJ365886675JP
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Home Disorders
Depression

Depression

Depression

Treatment of depression in Japan

Depression, or major depressive disorder (MDD) is a medical condition which characterizes in consistent loss of interest in life, low mood and self-esteem. Japanese government estimates that around 1.200.000 people in Japan suffer from this mental disorder, but as far not all of them ask for professional help, the actual number might be significantly more (厚生労働省. 平成30年版厚生労働白書. 2019; https://www.mhlw.go.jp/toukei_hakusho/hakusho/). The variety of symptoms makes finding out the right diagnosis and prescribing adequate medicines for depression quite complicated. Following symptoms are the most common:

  • Feeling sad, hopeless, lonely for a long period of time,
  • Inability to feel joy or satisfaction,
  • Not feeling better when receiving support from family or friends,
  • Irritation, anger or tearfulness upon unimportant matters,
  • Consistent tiredness and lack of energy,
  • Sleeping disturbances, including both insomnia and sleepiness,
  • Eating disorders, including lack of appetite and excessive uncontrolled eating,
  • Lack of concentration, memory troubles, troubled or slow thinking,
  • Anxiety,
  • Suicidal thoughts or attempts, thinking of death,
  • Unexplained physical pain or disorders.

Symptoms may also vary upon age and gender, for example, older people with depression may have symptoms similar to dementia, like forgetfulness or slow movements.

Treatment of the depression is a complex process, depending on the disease cause, progression level and patient’s desire to participate in certain activities. For earlier stages of major depressive disorder, the most effective ways to treat the disease are taking psychotherapy and changing lifestyles, like doing regular exercises, going for walks, following healthy diet and maintaining good sleep. However, as the disorder progresses, some chemical reactions in the brain make the recovery extremely difficult. In this case, the consulting doctor should help to treat the most adequate medicines for treatment of the depression.

Which medicines for depression should I choose?

Antidepressants mainly work on postsynaptic and presynaptic receptors in the brain. Selective serotonin reuptake inhibitors limit reabsorption of serotonin in the presynaptic cell, increasing its free extracellular level. Norepinephrine or noradrenaline reuptake inhibitors work in the similar way for norepinephrine and epinephrine, increasing adrenergic neurotransmission. Some of the medicines affect all the receptors listed. Also, there are tricyclic antidepressants targeting dopamine receptors and some medicine with mild opioid-like actions. The doctor in charge should help the patient to choose the adequate treatment according to disease, age and symptoms. Many of Japanese medicines for depression have their own unique features to be considered.

  • Cymbalta capsules are effective for the treatment of not only major depressive states, but also for various anxiety disorders and neurological pains,
  • Effexor capsules’ active ingredient binds to a broad spectrum of brain receptors, so usually this medicine can be used even for patients who don’t respond to other antidepressants,
  • Fluvoxamine maleate tablets help to treat Internet addiction and social phobia,
  • Trazodone tablets improve insomnia symptoms,
  • Sertraline tables are effective for the treatment of fear, avoidance and social phobia,
  • Lexapro tablets are particularly good for long-term use in adults over certain age.

Also, Japanese doctor often use a natural remedy called Yokukansan for alleviating the mild depression symptoms without side effects. It helps to treat low mood, insomnia, irritability and early dementia as well, so it is a great option for elder patients.

Atarax-P capsules 25 mg (hydroxyzine pamoate, Vistaril)
General information on Japanese Atarax-P capsules 25 mg (hydroxyzine pamoate, Vistaril) Packa..
USD 28.00
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Coreminal tablets 4 mg for stress and anxiety (Flutazolam)
General Information on Japanese Coreminal tablets 4 mg for stress and anxiety (Flutazolam)  ..
USD 27.00
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Cymbalta capsules 30 mg for depression and depressive states (duloxetine hydrochloride)
General information on Japanese Cymbalta capsules 30 mg for depression and depressive states (dul..
USD 459.00
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Effexor SR capsules 37.5 mg for depression and depressed state (Venlafaxine, antidepressant)
General information on Japanese Effexor SR capsules 37.5 mg for depression and depressed state (V..
USD 289.00
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Lexapro tablets 10 mg for depression and anxiety (Cipralex, escitalopram, antidepressant)
General information on Japanese Lexapro tablets 10 mg for depression and anxiety (Cipralex, escit..
USD 795.00
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Melex tablets 1 mg for anxiety and stress (Sedoxil, mexazolam)
General information on Japanese Melex tablets 1 mg for anxiety and stress (Sedoxil, mexozolam)&nb..
USD 49.00
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Restas tablets 2 mg for anxiety and stress control (flutoprazepam)
General information on Japanese Restas tablets 2 mg for anxiety and stress (flutoprazepam)  ..
USD 69.00
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Sertraline tablets 25 mg for depression, panic disorder and posttraumatic stress disorder (antidepressant, Zoloft)
General information on Japanese Sertraline tablets 25 mg for depression, panic disorder and postt..
USD 69.00
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Trazodone tablets 25 mg for depression and anxiety (Desirel, Reslin, Trittico, antidepressant)
General information on Japanese Trazodone tablets 25 mg for depression and anxiety (Desirel, Resl..
USD 22.00
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Tryptanol tablets 25 mg for depression (antidepressant)
General information on Japanese Tryptanol tablets 25 mg for depression (antidepressant)  &nb..
USD 45.00
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Yokukansan (stress relief, nervous tension, depression) 24 sachets
General Information on Yokukansan. One package contains 24 sachets. Daily dosage 2300 m..
USD 53.00
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Dear Customers!   IF YOU PAID BY WISE COM before MAY 3rd   AND STILL DID NOT RECEIVE PAYMENT CONFIRMATION FROM US -   Please contact us by email and advise Exact payout amount in EURO.   Our bank had a disruption during holidays, we can not see comments and references, we only see “WISE” and Amount in EURO for all payment received during holidays.   THE LIST OF THREE TRANSACTIONS IS BELOW:   237.90 EUR - APRIL 27th 924.20 EUR - APRIL 27th   236.17 EUR - APRIL 28th   Please kindly assist if you paid and help to identify payments.   Sincerely yours Japan Health Centre
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Reviews

John

Great product, original Japanese Lactis EL027826792JP
more ▶

Reviews

Mike

Good effect. I shall order again. Original made-in-japan package as promised EG401137451JP
more ▶

Reviews

May

Real Japanese laennec. Thank you! I shall order again. EJ377189782JP
more ▶

Reviews

Bob

Great effect! Got my hair back in 3 months. EG401137588JP
more ▶

Reviews

Nike

Lost 3 kilos since started to drink it last month. Great for fitness EG299855913JP
more ▶

Reviews

Any

Bought it for my son. Good effect and great service. EG299855961JP
more ▶

Reviews

Nya

Original touchi, fast delivery and good price. Thank you. EG401137156JP
more ▶

Reviews

Sam

Good medicine. Think it really helps me to fight cancer. EL025661542JP
more ▶

Reviews

John

3 times cheaper than in our country! And great effect for knees EJ365886698JP
more ▶

Reviews

Mike

Great thing to support diet. Lost 4 kilos for 6 weeks. Shall order more EJ365886675JP
more ▶