Trazodone tablets 25 mg for depression and anxiety (Desirel, Reslin, Trittico, antidepressant)
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General information on Japanese Trazodone tablets 25 mg for depression and anxiety (Desirel, Reslin, Trittico, antidepressant)
Package details: 100 tablets
Manufacturer: Kyowa Pharmaceutical Industry Co. Ltd., Japan
Active ingredients: trazodone hydrochloride (chemical formula C19H23Cl2N5O)
Medical effect: Trazodone tablets are effective for the treatment of depression and depressed state.
Contraindications and precautions: do not use for the following categories of patients:
- Trazodone tablets cannot be used for patients in the initial recovery period after myocardial infarction.,
- pregnant, possibly pregnant or breastfeeding women,
- patients with a heart disease or its history, glaucoma, urination difficulty, ocular hypertension,
- patients with convulsive disorders such as epilepsy or its history,
- patients with bipolar illness (also called manic-depressive illness), predisposition of organic brain disorder or schizophrenia, highly impulsive comorbid disorders, or suicidal thoughts/suicide attempt or its history.
As this medicine may cause sleepiness, the patient should avoid working at heights, operating dangerous machinery, or driving a car.
Refrain from taking alcohol while taking this medicine.
If any unusual mental symptoms (irritability, excitability, aggression, etc.) are observed, consult with your doctor. The patient and the patient’s family should require full explanation from their doctor before use.
If an allergic reaction occurs, stop taking the medicine and consult with your doctor. If you’re taking any other medication or receiving any other treatment, you have to consult with your doctor before use.
Dosage and administration
Start with taking 3-4 tablets (75-100 mg of the active ingredient) per day as an initial dose, dividing into one to several doses. Then the dosage may be gradually increased up to 8 tablets (200 mg) per day, in one to several divided doses. The doctor in charge may adjust the dosage according to patient’s disease, age or symptoms. If the dose is suddenly reduced or patient stops the medication, withdrawal symptoms (nausea, headache, dullness, anxiety, sleep disorder, etc.) may occur.
How effective are Trazodone tablets 25 mg from Japan for depression and anxiety (Desirel, Reslin, Trittico, antidepressant)?
Trazodone tablets work in multiple ways: as a mixed agonist and antagonist of various serotonin receptors, as an antagonist of adrenergic receptors, as a histamine H1 receptor antagonist, and as a serotonin reuptake inhibitor. The active component has a high bioavailability and is not sequestered into any tissue. Trazodone has anxiolytic properties, low cardiotoxicity, and relatively mild side effects.
Who should use Trazodone tablets 25 mg from Japan?
Trazodone tablets are effective for the treatment of depression and depressed state. Studies showed that trazodone is effective in both endogenous and nonendogenous patients, has a more pronounced action than the tricyclic antidepressants and helps to improve insomnia as well as alleviate depressive mood and decrease anxiety (A. F. Schatzberg. “Trazodone: A 5-Year Review of Antidepressant Efficacy”. Psychopathology, 1987, 20: 48–56).