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Orapenem fine granules 10% for children (tebipenem pivoxil, antibiotic)
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General information on Japanese Orapenem fine granules 10% for children (tebipenem pivoxil, antibiotic)
Package details: 120 packets * 0.5g
Manufacturer: Meiji Seika Pharma Co., Ltd., Japan
Active ingredient: tebipenem pivoxil (chemical formula C22H31N3O6S2)
Medical effect: Orapenem granules are effective for the treatment of the following diseases and conditions:
- otitis media,
- treatment of quinolone-resistant Enterobacteriaceae.
Contraindications and precautions: do not use for pregnant and breastfeeding women. Do not use for patients with renal disorder, poor ingestion or parenteral nutrition, or poor general status. Do not use for patients with a history of convulsive diseases such as epilepsy. Use with a great caution if the child or their parents or siblings are prone to allergic symptoms such as bronchial asthma, rash or hives.
If an allergic reaction occurs, stop taking the medicine and consult with your doctor. If you’re taking any other medication, please consult with your doctor before use.
Dosage and administration of Orapenem fine granules 10% from Japan for children (tebipenem pivoxil, antibiotic)
For children: Take 0.04 gram per kilogram of body weight 2 times a day, after meals. The consulting doctor may increase the dosage up to 0.06 g/kg if needed. Standard duration of administration is for 7 days or less.
How effective are Orapenem fine granules 10% from Japan for children (tebipenem pivoxil, antibiotic)?
Orapenem granules contain tebipenem pivoxil, first orally available antibiotic of a carbapenem class. It is rapidly converted to the active form in plasma and enterocytes and has a broad spectrum of action. Orapenem granules are particularly known for their ability to treat multidrug-resistant Gram-negative pathogens, including quinolone-resistant Enterobacteriaceae.
Who should take Orapenem fine granules 10% from Japan?
Orapenem granules are effective for the treatment of pneumonia, otitis media and sinusitis in pediatric patients. This medicine can be used even for the bacteria resistant to other antibiotics. Studies showed that in children with community-acquired pneumonia tebipenem significantly lowers body temperature on the day following initial administration and reduces leukocyte counts and C-reactive protein levels by day 2-4 of the treatment (H. Sakata, H. Kuroki et al. “Pediatric community-acquired pneumonia treated with a three-day course of tebipenem pivoxil”. Journal of Infection and Chemotherapy. 2017, May;23(5): 307-311).