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Musredo tablets 75 mg for renal anemia (molidustat sodium)
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Availability : 14
USD 859.00
General information on Japanese Musredo tablets 75 mg for renal anemia (molidustat sodium)
Package details: 100 tablets
Manufacturer: Bayer Yakuhin, Ltd., Japan
Active ingredients: molidustat sodium (chemical formula C13H14N8O2)
Medical effect: Musredo tablets are effective for increasing the number of red blood cells in patients with renal anemia.
Contraindications and precautions: do not use for the following categories of patients:
- pregnant or possible pregnant women,
- breastfeeding women,
- patients with hypertension,
- patients with cerebral infarction, myocardial infarction or pulmonary embolism or a history of those.
If an allergic reaction occurs, stop taking the medicine and consult with your doctor. If you’re taking any other medication or receiving any other treatment, you have to consult with your doctor before use.
Periodical blood tests to measure concentrations of hemoglobin, etc. should be performed. Patients need to take iron to get an adequate efficacy.
Female patients should use an adequate contraception while taking this medicine and for 2 weeks after finishing the course of treatment.
Dosage and administration of Musredo tablets 75 mg from Japan for renal anemia (molidustat sodium)
For patients with chronic kidney disease but not on dialysis and untreated by erythropoiesis stimulating agent: for adults, start with taking 25 mg of active ingredient at a time, once a day after meal, as an initial dose. Then the doctor in charge may increase the dosage according to symptoms. But the maximum single dose of 200 mg should not be exceeded.
For patients with chronic kidney disease but not on dialysis and switching from erythropoiesis stimulating agent: for adults, start with 25-50 mg of an active ingredient at a time, once a day after meal. Then the doctor in charge may increase the dosage according to symptoms. But the maximum single dose of 200 mg should not be exceeded.
For patients on dialysis: for adults, start taking 75 mg of the active ingredient at a time, once a day after meal. Then the doctor in charge may increase the dosage according to symptoms. But the maximum single dose of 200 mg should not be exceeded.
Please note that this preparation contains 75 mg of molidustat in one tablet.
How effective are Musredo tablets 75 mg from Japan for renal anemia (molidustat sodium)?
Musredo tablets contain molidustat sodium, an HIF prolyl-hydroxylase inhibitor. It works by activating hypoxia inducible factor (HIF) pathways and boosting the production of erythropoietin which stimulates producing red blood cells.
Who should use Musredo tablets 75 mg from Japan?
Musredo tablets increase the number of red blood cells and improve anemia in patients with renal anemia. Studies showed that is well-tolerated, effective and safe for both patients receiving and not receiving dialysis, even when being administrated for a long period of time (T. Akizawa, I. C. Macdougall et al. “Long-Term Efficacy and Safety of Molidustat for Anemia in Chronic Kidney Disease: DIALOGUE Extension Studies”. American journal of nephrology, 2019; 49(4): 271-280).