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John

Great product, original Japanese Lactis EL027826792JP
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Mike

Good effect. I shall order again. Original made-in-japan package as promised EG401137451JP
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May

Real Japanese laennec. Thank you! I shall order again. EJ377189782JP
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Bob

Great effect! Got my hair back in 3 months. EG401137588JP
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Nike

Lost 3 kilos since started to drink it last month. Great for fitness EG299855913JP
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Any

Bought it for my son. Good effect and great service. EG299855961JP
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Nya

Original touchi, fast delivery and good price. Thank you. EG401137156JP
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Sam

Good medicine. Think it really helps me to fight cancer. EL025661542JP
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John

3 times cheaper than in our country! And great effect for knees EJ365886698JP
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Mike

Great thing to support diet. Lost 4 kilos for 6 weeks. Shall order more EJ365886675JP
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Home Disorders Anemia
Evrenzo tablets 50 mg for renal anemia (roxadustat)
Evrenzo tablets 50 mg for renal anemia (roxadustat)
Evrenzo tablets 50 mg for renal anemia (roxadustat)
Product Code Evrenzo
Availability 12
Price USD 598.00
Qty
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Evrenzo tablets 50 mg for renal anemia (roxadustat)

Product Code : Evrenzo

Availability : 12

USD 598.00

Buy now

General information on Japanese Evrenzo tablets 50 mg for renal anemia (roxadustat)

Package details: 30 tablets

Manufacturer: Astellas Pharma Inc., Japan

Active ingredient: roxadustat (chemical formula C19H16N2O5)

Medical effect: Evrenzo tablets are effective for the treatment of anemia attributable to renal diseases.

Contraindications and precautions: do not use for the following categories of patients:

  • patients with a history of cerebral infarction, myocardial infarction or pulmonary embolism,
  • patients with hypertension,
  • pregnant or possibly pregnant women,
  • breastfeeding women.

If an allergic reaction occurs, stop taking the medicine and consult with your doctor. If you’re taking any other medication or receiving any other treatment, you have to consult with your doctor before use.

Serum concentrations of hemoglobin should be checked periodically while taking this medicine. Also, the patient needs to take iron to get an adequate efficacy.

In order to avoid a possibility of pregnancy, female patients should use adequate contraception while taking this medicine and for a certain period of time after the last dose of this medicine.

As the lacteal transfer has been reported in animal experiments, female patients should avoid breastfeeding from the start to 28 days after the last dose of this medicine.

Dosage and administration of Evrenzo tablets 50 mg from Japan for renal anemia (roxadustat)

For patients untreated by erythropoiesis stimulating agent: for adults, start with 1 tablet (50 mg of roxadustat) at a time, 3 times a week, at intervals of 2 to 3 days (e.g. on Monday/Wednesday/Friday or on Tuesday/Thursday/Saturday). Thereafter, the dosage may be adjusted by doctor in charge according to the condition of the patient. The maximum single dose is 3.0 mg/kg.

For patients switching from erythropoiesis stimulating agent: for adults, start with either 70 mg or 100 mg of the active ingredient at a time, 3 times a week, at intervals of 2 to 3 days (e.g. on Monday/Wednesday/Friday or on Tuesday/Thursday/Saturday). Thereafter, the dosage may be adjusted by the doctor in charge according to the condition of the patient. The maximum single dose is 3.0 mg/kg.

Please note that this medicine contains 50 mg of the active ingredient in a tablet.

How effective are Evrenzo tablets 50 mg from Japan for renal anemia (roxadustat)?

Evrenzo tablets contain Roxadustat, a new inhibitor of HIF (hypoxia inducible factor), transcription factor that responds to decreases in available oxygen in the cellular environment. It works by activating HIF pathways and degrading HIF, by this, increasing endogenous production of erythropoietin, a glycoprotein cytokine secreted mainly by the kidney in response to cellular hypoxia. As the result, Evrenzo tablets stimulate red blood cell production (erythropoiesis) and production of hemoglobin, increase the increase the number of red blood cells and improve the symptoms of renal anemia.

Who should take Evrenzo tablets 50 mg from Japan?

At first, roxadustat was approved for using in patients undergoing dialysis, but since 2020 it was also approved in Japan for patients not receiving dialysis. Multiple studies showed that roxadustat leads to a numerically greater mean change in hemoglobin level, increases the transferrin level, decreases total cholesterol and low-density lipoprotein cholesterol level (T. Akizawa, M. Ueno et al. “Oral roxadustat three times weekly in ESA-naive and ESA-converted patients with anemia of chronic kidney disease on hemodialysis”. Therapeutic apheresis and dialysis, 2020, December, 24(6): 628-641). That’s why Evrenzo tablets are effective for the treatment of anemia attributable to renal diseases.

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Dear Customers!   IF YOU PAID BY WISE COM before MAY 3rd   AND STILL DID NOT RECEIVE PAYMENT CONFIRMATION FROM US -   Please contact us by email and advise Exact payout amount in EURO.   Our bank had a disruption during holidays, we can not see comments and references, we only see “WISE” and Amount in EURO for all payment received during holidays.   THE LIST OF THREE TRANSACTIONS IS BELOW:   237.90 EUR - APRIL 27th 924.20 EUR - APRIL 27th   236.17 EUR - APRIL 28th   Please kindly assist if you paid and help to identify payments.   Sincerely yours Japan Health Centre
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Reviews

John

Great product, original Japanese Lactis EL027826792JP
more ▶

Reviews

Mike

Good effect. I shall order again. Original made-in-japan package as promised EG401137451JP
more ▶

Reviews

May

Real Japanese laennec. Thank you! I shall order again. EJ377189782JP
more ▶

Reviews

Bob

Great effect! Got my hair back in 3 months. EG401137588JP
more ▶

Reviews

Nike

Lost 3 kilos since started to drink it last month. Great for fitness EG299855913JP
more ▶

Reviews

Any

Bought it for my son. Good effect and great service. EG299855961JP
more ▶

Reviews

Nya

Original touchi, fast delivery and good price. Thank you. EG401137156JP
more ▶

Reviews

Sam

Good medicine. Think it really helps me to fight cancer. EL025661542JP
more ▶

Reviews

John

3 times cheaper than in our country! And great effect for knees EJ365886698JP
more ▶

Reviews

Mike

Great thing to support diet. Lost 4 kilos for 6 weeks. Shall order more EJ365886675JP
more ▶