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General information on Japanese tablets Zacras for hypertension
Package details: 100 tablets
Manufacturer: Takeda Pharmaceutical Company, Japan
Active ingredient: Azilsartan 20 mg, Amlodipine besilate 5 mg
Medical effect: Zacras tablets are effective for the treatment of the hypertension by reducing resistance of peripheral blood vessels.
Contraindications and precautions:
Zacras tablets cannot be used in the following categories of patients:
- patients with renal or liver disorders,
- patients with cerebrovascular disorder or hyperkalemia,
- patients receiving hemodialysis,
- patients under low-salt diet treatment,
- preoperative patients,
- children,
- pregnant, possibly pregnant or breastfeeding women.
Dosage and administration of Zacras anti-hypertension tablets
Take 1 tablet 1 time a day. If you missed a dose, do not take the double dose and do not take additional dose if the next regular intake time is in less than 8 hours.
About effects and studies of Japanese tablets Zacras for high blood pressure
Zacras tablets from hypertension from Japan contain two active ingredients, azilsartan and amlodipine besilate. The medication works by blocking angiotensin II receptor and affecting calcilum channel of smooth muscle of blood vessels. By this, Zacras tablets reduce resistance of peripheral blood vessel and lowers systolic and diastolic blood pressure. Studies show that combination of azilsartan and amlodipine is effective, safe and has very few side effects (K. Motozato, S. Miura et al. Efficacy and Safety of a Single-Pill Fixed-Dose Combination of Azilsartan and Amlodipine. Journal of Clinical Medicine Research. 2016 Dec; 8(12): 888–892).