Vencoll combination tablets for constipation (docusate, dioctyl sulfosuccinate, casanthranol)

General information on Japanese Vencoll combination tablets for constipation (docusate, dioctyl sulfosuccinate, casanthranol)

Package details: 100 tablets

Manufacturer: Nichi-Iko Pharmaceutical Co., Ltd., Japan

Active ingredients: dioctyl sodium sulfosuccinate (chemical formula C20H37NaO7S), casanthranol (chemical formula C21H22O10)

Medical effect: Vencoll combination tablets are effective for treatment of constipation and elimination of intestinal contents in abdominal organ test or perioperative period.

Contraindications and precautions: do not use for the following categories of patients:

• Pregnant, possibly pregnant or breastfeeding women should not use Vencoll combination tablets,
• Patients who are suspected of having acute abdomen,
• Patients who are diagnosed with a severe hard stool,
• Patients with a spastic constipation.

Please note that urine may change color to yellow-brown or red.

If an allergic reaction occurs, stop taking the medicine and consult with your doctor. If you’re taking any other medication or receiving any other treatment, you have to consult with your doctor before use.

Dosage and administration

For adults, take 5-6 tablets at a time, before bedtime, or 6 tablets a day, dividing into 2-3 doses. This medicine should be taken with a large amount of water.

The doctor in charge may adjust the dosage according to age and symptoms of the patient.

How effective are Vencoll combination tablets from Japan for constipation (docusate, dioctyl sulfosuccinate, casanthranol)?

Vencoll combination tablets have two main ingredients, casanthranol and dioctyl sulfosuccinate, also known as docusate. Casanthranol increases peristalsis via direct action in the myenteric plexus, thus, improving bowel movements. Docusate softens stool by absorbing more water and slightly inhibiting fluid absorption in small intestine.

Who should use Vencoll combination tablets from Japan?

Vencoll combination tablets are effective for treatment of constipation and elimination of intestinal contents in abdominal organ test or perioperative period. This medicine can be used for patients receiving opioid medications, inducing constipation (D. Ramkumar, S. S. Rao. "Efficacy and safety of traditional medical therapies for chronic constipation: systematic review". The American Journal of Gastroenterology, 2005, 100 (4): 936–71).