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Digestion, Stomach, GIT

Reviews

John

Great product, original Japanese Lactis EL027826792JP
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Reviews

Mike

Good effect. I shall order again. Original made-in-japan package as promised EG401137451JP
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Reviews

May

Real Japanese laennec. Thank you! I shall order again. EJ377189782JP
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Reviews

Bob

Great effect! Got my hair back in 3 months. EG401137588JP
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Reviews

Nike

Lost 3 kilos since started to drink it last month. Great for fitness EG299855913JP
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Reviews

Any

Bought it for my son. Good effect and great service. EG299855961JP
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Reviews

Nya

Original touchi, fast delivery and good price. Thank you. EG401137156JP
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Reviews

Sam

Good medicine. Think it really helps me to fight cancer. EL025661542JP
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Reviews

John

3 times cheaper than in our country! And great effect for knees EJ365886698JP
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Reviews

Mike

Great thing to support diet. Lost 4 kilos for 6 weeks. Shall order more EJ365886675JP
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Home Drugs and Supplements Digestion, Stomach, GIT
Goofice tablets 5 mg (hronic constipation)
Goofice tablets 5 mg (hronic constipation)
Product Code Chronic constipation
Availability 12
Price USD 259.00
Qty
Buy now Guarantee Contact as

Goofice tablets 5 mg (hronic constipation)

Product Code : Chronic constipation

Availability : 12

USD 259.00

Buy now

General information about Japanese Goofice tablets 5 mg

Package details: 100 tablets

Manufacturer: EA Pharma, Japan.

Active ingredient: Elobixibat hydrate, 5 mg in each tablet

Medical effect: Goofice tablets 5 mg from Japan have following medical effects:

  • suppressing reabsorption of bile acids,
  • increases the flow of bile acids to the colon,
  • promoting moisture and electrolyte secretion to the colon,
  • enhancing bowel movement,
  • therapeutic effect on chronic constipation.

Contraindications and precautions:

Do not use in children, pregnant or breastfeeding women. Cannot be used for patients with intestinal obstruction due to tumor or hernia. If an allergic reaction occurs, discontinue use. When used with other drugs, be sure to consult with your doctor as the elobixibat hydrate may interact with other ingredients.

Dosage and Administration of Japanese Goofice tablets against constipation:

Take 2 tablets once a day, before meal. The consulting doctor may adjust the dosage but the maximum of 3 tablets a day shall never be exceeded. 

About the effectiveness of Goofice tablets 5 mg from Japan

Goofice tablets 5 mg from Japan are effective against chronic constipation, caused by different reasons (excluding constipation due to organic diseases). This medicine is considered to be world’s first bile acid transporter inhibitor. EA Pharma has published the results of clinical studies, proving that Goofice tablets help with treatment of chronic constipation (EA Pharma Co., Ltd. and Mochida Pharmaceutical Co., Ltd. announce the results of phase 3 study of AJG533 for chronic constipation conducted in Japan – Primary endpoint met in patients with chronic constipation. Sep 2016. https://www.eapharma.co.jp/en/news/2016/0930.pdf ; Results from Two Phase 3 Clinical Trials of Chronic Constipation Treatment “GOOFICE® 5mg Tablet” Published in The Lancet Gastroenterology & Hepatology. Jul 2018. https://www.eapharma.co.jp/en/news/2018/0709.pdf ). Despite this is relatively new medicine, researchers all over the world have already reported great potential of the biloxibat (Andres Acosta and Michael Camiller. “Elobixibat and its potential role in chronic idiopathic constipation”. Therapeutic Advances in Gastroenterology, 2014 Jul; 7(4): 167–175; Yuji Kumagai, Hideki Amano et al. “Effect of single and multiple doses of elobixibat, an ileal bile acid transporter inhibitor, on chronic constipation: A randomized controlled trial”. British Journal of Clinical Pharmacology, 2018 Oct; 84(10): 2393–2404.). 

Frances | 3 reviews
I did number two once in 3 or 4 dys and always felt bloated. These tablets improved my bowel a lot, now I do it once in 2 days or even every day!
Summer | 3 reviews
Improves bowel movement
May | 3 reviews
Very effective against constipation, no side effects

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News

Shipping to USA, EU, Asia, Oceania and South America in October

Notification from 1st October 2021 - Regarding shipping in Pandemic and Japan Post Stop Act. Dear Customers!   WE CAN SHIP to USA, EU, UAE, Israel, Australia, New Zealand, Canada, Hong-Kong, China, Korea, Vietnam, Mexico, Brazil and all other countries!   Japan Post imposed restrictions on shipping to most of other coutnries. Situation changes eevry day, you can find latest news here - https://www.post.japanpost.jp/int/information/index_en.html Please use search on page to find your country.   IF JAPAN POST DOES NOT SHIP OR SHIPS BY SURFACE MAIL ONLY WE CAN SHIP BY COURIER.   For shiping by Japan Post check this link with full list of countries https://www.post.japanpost.jp/int/information/overview_en.html For shipping by Сourier check table below or contact us as situation changes every day.   SEE TABLE WITH MOST POPULAR DESTINATIONS BELOW. SEE COMMENTS BELOW TABLE IF YOU CAN NOT FIND YOUR COUNTRY -- CONTACT US! WE CAN SHIP TO YOUR COUNTRY. Shipping type Economy Mail ** Express Service Methods: * SURFACE AIRMAIL Courier05 *** EMS  Argentina NO YES YES YES Armenia YES  YES YES NO Australia YES  YES YES NO Austria YES  YES YES YES Azerbaijan YES  YES YES NO Belarus YES  YES YES NO Belgium YES  YES YES YES Brazil YES NO YES NO Bulgaria YES  YES YES YES Canada YES  YES YES NO Chile NO YES YES YES China YES  YES YES YES Colombia NO YES YES YES Congo YES NO YES NO Costa Rica YES NO YES NO Croatia YES  YES YES YES Cyprus NO YES YES YES Czech YES  YES YES YES Denmark YES  YES YES YES Ecuador NO NO YES NO Egypt YES YES YES NO Estonia YES  YES YES YES Finland YES  YES YES YES France YES  YES YES YES Georgia YES NO YES NO Germany YES  YES YES YES Great Britain YES  YES YES YES Greece YES  NO YES NO Hungary YES  YES YES YES India YES  NO YES NO Indonesia YES  YES YES YES Iran / Iraq NO YES  NO YES Ireland YES YES YES YES Israel YES YES YES YES Italy YES  YES YES YES Kazakhstan YES  NO NO NO Kenya NO YES YES YES Laos YES NO YES NO Latvia YES  YES YES YES Liechtenstein YES  YES YES YES Lithuania YES  YES YES YES Luxemurbg YES  YES YES YES Malaysia YES  NO YES NO Mexico YES  YES YES YES Moldova YES NO YES NO Mongolia NO NO YES NO New Zealand YES  YES YES YES Norway YES  YES YES YES Pakistan NO YES YES YES Panama NO NO YES NO Peru YES NO YES NO Poland YES  YES YES YES Portugal YES  YES YES YES Romania YES  NO YES NO Russia YES NO NO (ASK US) NO Saudi Arabia YES NO YES NO Serbia YES  YES YES NO Slovakia YES  YES YES NO Spain YES  YES YES YES Sri Lanka YES  YES YES YES Sweden YES  YES YES YES Switzerland YES  YES YES YES Tajikistan YES NO YES NO Turkey YES  YES YES YES UAE (Dubai) YES  YES YES YES Ukraine YES YES NO YES USA YES  YES* YES NO Uzbekistan YES NO YES NO Vietnam YES  YES YES YES           * We select appropriate available method. If you need specific method contact us. ** Economy mail is shipped by Air if airmail is available, if not we ship by Surface mail. There are restrictions applied by Japan Post. *** Courier-05, shipping for parcels with tablets up to 5 boxes (most cases), vials 10-20 pcs drops up to 0,5 kg in weight. Can ship to specific regions/cities, please check before order. IF YOU DO NOT SEE COUNTRY ON LIST, CONTACT US!   USA: - EXPRESS SERVICE. We ship by express, Delivery takes 8-12 days.  - AIRMAIL MAIL. If you prefer economy mail, we ship by standard airmail, takes 2-4 weeks, no tracking, only local number in Japan, Rate starts at 29 usd, free shipping for orders above 400 usd and 2 kg. If you can wait use this method.   EU - EUROPE We ship as usual to all countries besides Greece, Romania, Moldova and Russia.  For Romania, Greece and Moldova: We ship using express service to all other countries in EU at the moment. Or by surface mail.   ASIA - SINGAPORE, HONG KOG, KOREA, TAIWAN, THAILAND, VIETNAM, MALAYSIA, PHILIPPINES. We ship as usual (with possible delays) to these countries   SHIPPING TO CHINA. We ship as usual by EMS or Airmail.    SHIPPING TO UAE and ISRAEL. We ship as usual by EMS or Airmail.    SHIPPING TO INDIA. - WE CAN SHIP BY COURIER. We can ship by express method almost everything. Delivery takes 8-14 days. USE EXPRESS METHOD. - WE SHIP BY SURFACE MAIL. This takes 6-8 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail.   OCEANIA - AUSTRALIA. NEW ZEALAND To Australia: - EXPRESS SERVICE. We ship by express, Delivery takes 8-12 days.  - AIRMAIL MAIL. If you prefer economy mail, we ship by surface mail, takes 2-4 weeks, no tracking, only local number in Japan, Rate starts at 29 usd, free shipping for orders above 400 usd and 2 kg. If you can wait use this method. TO NEW ZEALAND - WE SHIP AS USUAL    BRAZIL - WE CAN SHIP BY COURIER. We can ship by express method almost everything. Delivery takes 8-14 days. USE EXPRESS METHOD. - WE SHIP BY SURFACE MAIL. This takes 10-15 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail.   CANADA - EXPRESS SERVICE. We ship by express, Delivery takes 8-12 days.  - AIRMAIL MAIL. If you prefer economy mail, we ship by surface mail, takes 2-4 weeks, no tracking, only local number in Japan, Rate starts at 29 usd, free shipping for orders above 400 usd and 2 kg. If you can wait use this method.   UKRAINE, KAZAKHSTAN, RUSSIA, BELARUS. - WE CAN SHIP TO UKRANE and BELARUS as usual by  AIRMAIL WITH POSSIBLE DELAYS. EMS and courier is available for Ukraine.  - Only surface mail is allowed for Russia  and Kazakhstan due to strict customs control for all other methods. We can ship by Fedex at your responsibility.
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Reviews

John

Great product, original Japanese Lactis EL027826792JP
more ▶

Reviews

Mike

Good effect. I shall order again. Original made-in-japan package as promised EG401137451JP
more ▶

Reviews

May

Real Japanese laennec. Thank you! I shall order again. EJ377189782JP
more ▶

Reviews

Bob

Great effect! Got my hair back in 3 months. EG401137588JP
more ▶

Reviews

Nike

Lost 3 kilos since started to drink it last month. Great for fitness EG299855913JP
more ▶

Reviews

Any

Bought it for my son. Good effect and great service. EG299855961JP
more ▶

Reviews

Nya

Original touchi, fast delivery and good price. Thank you. EG401137156JP
more ▶

Reviews

Sam

Good medicine. Think it really helps me to fight cancer. EL025661542JP
more ▶

Reviews

John

3 times cheaper than in our country! And great effect for knees EJ365886698JP
more ▶

Reviews

Mike

Great thing to support diet. Lost 4 kilos for 6 weeks. Shall order more EJ365886675JP
more ▶