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Digestion, Stomach, GIT

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John

Great product, original Japanese Lactis EL027826792JP
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Mike

Good effect. I shall order again. Original made-in-japan package as promised EG401137451JP
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May

Real Japanese laennec. Thank you! I shall order again. EJ377189782JP
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Bob

Great effect! Got my hair back in 3 months. EG401137588JP
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Nike

Lost 3 kilos since started to drink it last month. Great for fitness EG299855913JP
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Any

Bought it for my son. Good effect and great service. EG299855961JP
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Nya

Original touchi, fast delivery and good price. Thank you. EG401137156JP
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Sam

Good medicine. Think it really helps me to fight cancer. EL025661542JP
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John

3 times cheaper than in our country! And great effect for knees EJ365886698JP
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Mike

Great thing to support diet. Lost 4 kilos for 6 weeks. Shall order more EJ365886675JP
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Home Japanese Supplements Digestion, Stomach, GIT
Goofice tablets 5 mg (hronic constipation)
Goofice tablets 5 mg (hronic constipation)
Product Code Chronic constipation
Availability 12
Price USD 259.00
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Goofice tablets 5 mg (hronic constipation)

Product Code : Chronic constipation

Availability : 12

USD 259.00

Buy now

General information about Japanese Goofice tablets 5 mg

Package details: 100 tablets

Manufacturer: EA Pharma, Japan.

Active ingredient: Elobixibat hydrate, 5 mg in each tablet

Medical effect: Goofice tablets 5 mg from Japan have following medical effects:

  • suppressing reabsorption of bile acids,
  • increases the flow of bile acids to the colon,
  • promoting moisture and electrolyte secretion to the colon,
  • enhancing bowel movement,
  • therapeutic effect on chronic constipation.

Contraindications and precautions:

Do not use in children, pregnant or breastfeeding women. Cannot be used for patients with intestinal obstruction due to tumor or hernia. If an allergic reaction occurs, discontinue use. When used with other drugs, be sure to consult with your doctor as the elobixibat hydrate may interact with other ingredients.

Dosage and Administration of Japanese Goofice tablets against constipation:

Take 2 tablets once a day, before meal. The consulting doctor may adjust the dosage but the maximum of 3 tablets a day shall never be exceeded. 

About the effectiveness of Goofice tablets 5 mg from Japan

Goofice tablets 5 mg from Japan are effective against chronic constipation, caused by different reasons (excluding constipation due to organic diseases). This medicine is considered to be world’s first bile acid transporter inhibitor. EA Pharma has published the results of clinical studies, proving that Goofice tablets help with treatment of chronic constipation (EA Pharma Co., Ltd. and Mochida Pharmaceutical Co., Ltd. announce the results of phase 3 study of AJG533 for chronic constipation conducted in Japan – Primary endpoint met in patients with chronic constipation. Sep 2016. https://www.eapharma.co.jp/en/news/2016/0930.pdf ; Results from Two Phase 3 Clinical Trials of Chronic Constipation Treatment “GOOFICE® 5mg Tablet” Published in The Lancet Gastroenterology & Hepatology. Jul 2018. https://www.eapharma.co.jp/en/news/2018/0709.pdf ). Despite this is relatively new medicine, researchers all over the world have already reported great potential of the biloxibat (Andres Acosta and Michael Camiller. “Elobixibat and its potential role in chronic idiopathic constipation”. Therapeutic Advances in Gastroenterology, 2014 Jul; 7(4): 167–175; Yuji Kumagai, Hideki Amano et al. “Effect of single and multiple doses of elobixibat, an ileal bile acid transporter inhibitor, on chronic constipation: A randomized controlled trial”. British Journal of Clinical Pharmacology, 2018 Oct; 84(10): 2393–2404.). 

Frances | 3 reviews
I did number two once in 3 or 4 dys and always felt bloated. These tablets improved my bowel a lot, now I do it once in 2 days or even every day!
Summer | 3 reviews
Improves bowel movement
May | 3 reviews
Very effective against constipation, no side effects

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News

Shipping to USA, EU, Asia, Oceania and South America in November

Dear Customers! We ship to USA, to EU, to almost all countries by Japan Post OR Express Courier Service! Japan Post imposed restrictions on shipping to USA, EU and most of other coutnries. Situation changes every day. Please check this link for details on each country by Japan Post. https://www.post.japanpost.jp/int/information/overview_en.html We can ship to Most Countries. Please ask us on detail.  WE STILL CAN SHIP TO MOST COUNTRIES - SEE DETAILS BELOW OR CONTACT US IF YOU HAVE QUESTIONS!   USA: - EXPRESS SERVICE. We ship everything but placenta vials. Delivery takes 6-10 days.  - SURFACE MAIL. We ship all other items (vials), takes 7-9 weeks or more, we offer tracking, Rate starts at 19-29 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail.   EU - EUROPE We ship as usual (with possible delays) to the countries below (Alphabetic order):  Austria, Belgium, Bulgaria, Croatia, Czech, Denmark, Estonia, France (Monaco), Germany, Hungary, Italy, Latvia, Lithuania, Luxembourg, Netherlands (Holland), Norway, Poland, Portugal, Serbia, Slovenia, Spain, Sweden,     For other coutnries in Europe (Romania, Greece, Ukraine etc): We ship using express service to all other countries in EU at the moment. We can ship by express method for tablets and flat supplements in total weight not exceeding 0,5 kg. We ship in 7-12 business days. Delivery takes 6-10 days. USE EXPRESS METHOD. We can ship using surface mail. This takes 4-6 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail.   ASIA - SINGAPORE, HONG KOG, KOREA, PHILIPPINES, TAIWAN, THAILAND, VIETNAM, MALAYSIA, PHILIPPINES. We ship as usual (with possible delays) to these countries   SHIPPING TO CHINA. We ship as usual by EMS or Surface mail.    SHIPPING TO INDIA. - WE STILL CAN SHIP TABLETS/CAPSULES. We can ship by express method for tablets and flat supplements in total weight not exceeding 0,5 kg. We ship in 7-12 business days. Delivery takes 8-14 days. USE EXPRESS METHOD. - WE SHIP BY SURFACE MAIL. This takes 4-6 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail.   OCEANIA - AUSTRALIA. NEW ZEALAND To Australia: - WE STILL CAN SHIP TABLETS/CAPSULES. We can ship by express method for tablets and flat supplements in total weight not exceeding 0,5 kg. We ship in 7-12 business days. Delivery takes 8-14 days. USE EXPRESS METHOD. - WE SHIP BY SURFACE MAIL. This takes 4-6 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail. TO NEW ZEALAND - WE SHIP AS USUAL    BRAZIL - WE STILL CAN SHIP TABLETS / CAPSULES / EYE DROPS. We can ship by express method for tablets and flat supplements in total weight not exceeding 0,5 kg. We ship in 7-12 business days. Delivery takes 8-14 days. USE EXPRESS METHOD. - WE SHIP BY SURFACE MAIL. This takes 4-6 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail.   CANADA We ship as usual with delays due to reduced number of flights.   RUSSIA, UKRAINE, KAZAKHSTAN. - TO RUSSIA  WE SHIP ONLY BY SURFACE MAIL. This takes 5-6 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail. - TO UKRAINE WE SHIP BY COURIER MAIL OR BY SURFACE MAIL.  - WE CAN SHIP TO KAZAKHSTAN BY AIRMAIL WITH DELAYS. 
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Reviews

John

Great product, original Japanese Lactis EL027826792JP
more ▶

Reviews

Mike

Good effect. I shall order again. Original made-in-japan package as promised EG401137451JP
more ▶

Reviews

May

Real Japanese laennec. Thank you! I shall order again. EJ377189782JP
more ▶

Reviews

Bob

Great effect! Got my hair back in 3 months. EG401137588JP
more ▶

Reviews

Nike

Lost 3 kilos since started to drink it last month. Great for fitness EG299855913JP
more ▶

Reviews

Any

Bought it for my son. Good effect and great service. EG299855961JP
more ▶

Reviews

Nya

Original touchi, fast delivery and good price. Thank you. EG401137156JP
more ▶

Reviews

Sam

Good medicine. Think it really helps me to fight cancer. EL025661542JP
more ▶

Reviews

John

3 times cheaper than in our country! And great effect for knees EJ365886698JP
more ▶

Reviews

Mike

Great thing to support diet. Lost 4 kilos for 6 weeks. Shall order more EJ365886675JP
more ▶