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Digestion, Stomach, GIT

Reviews

John

Great product, original Japanese Lactis EL027826792JP
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Reviews

Mike

Good effect. I shall order again. Original made-in-japan package as promised EG401137451JP
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Reviews

May

Real Japanese laennec. Thank you! I shall order again. EJ377189782JP
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Reviews

Bob

Great effect! Got my hair back in 3 months. EG401137588JP
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Reviews

Nike

Lost 3 kilos since started to drink it last month. Great for fitness EG299855913JP
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Reviews

Any

Bought it for my son. Good effect and great service. EG299855961JP
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Reviews

Nya

Original touchi, fast delivery and good price. Thank you. EG401137156JP
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Reviews

Sam

Good medicine. Think it really helps me to fight cancer. EL025661542JP
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Reviews

John

3 times cheaper than in our country! And great effect for knees EJ365886698JP
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Reviews

Mike

Great thing to support diet. Lost 4 kilos for 6 weeks. Shall order more EJ365886675JP
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Home Japanese Supplements Digestion, Stomach, GIT
Linzess tablets 0.25 mg for constipation (Constella)
Linzess tablets 0.25 mg for constipation (Constella)
Linzess tablets 0.25 mg for constipation (Constella)
Product Code Linzess
Availability 15
Price USD 219.00
Qty
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Linzess tablets 0.25 mg for constipation (Constella)

Product Code : Linzess

Availability : 15

USD 219.00

Buy now

General information on Japanese Linzess tablets 0.25 mg for constipation     

Package details: 100 tablets

Manufacturer: Astellas Pharma Inc., Japan

Active ingredient: linaclotide (chemical formula C59H79N15O21S6)

Medical effect: Linzess tablets are effective for the treatment of the following diseases and conditions:

  • hypersensitivity in the large intestine,
  • abdominal pain and discomfort,
  • constipation-predominant irritable bowel syndrome,
  • chronic constipation.

Contraindications and precautions: do not use in pregnant or breastfeeding women. Do not use in patients who have, or are suspected of having, mechanical intestinal obstruction.

If an allergic reaction occurs, stop using the medication and consult with your doctor. If you’re taking any other medication, please consult with your doctor before use.

As this medicine is hygroscopic, take out the tablet from the sheet only just before taking the medicine. Do not leave naked unwrapped tablets or store them in a different container.

Dosage and administration of Linzess tablets 0.25 mg from Japan for constipation (Constella)

For adults, take 2 tablets 1 time a day before meals. The dosage may be reduced to 1 tablet depending on the symptoms.

The dosage may be adjusted by the consulting doctor according to age, body weight and symptoms.

How effective are Japanese Linzess tablets 0.25 mg for constipation?

Linzess tablets contain linaclotide, a synthetic tetradecapeptide mimic of endogenous guanylin and uroguanylin. It works by activating the guanylate cyclase C receptor on the surface of the intestinal epithelium. By this, Linzess tablets promote water secretion in the intestine, reduce pain by decreasing action of colonic sensory neurons and activate colonic motor neurons, which increases smooth muscle contraction. As a result, Linzess tablets from Japan effectively promote defecation.

Who should use Linzess tablets 0.25 mg from Japan (Constella)?

Linzess tablets are used for the treatment of the chronic constipation of unknown genesis and irritated bowel syndrome expressed predominantly in constipation. In general, linaclotide is a safe and effective medicine, it reduces pain and provides a physiologically sound approach to treatment of the multiple and complex symptoms of irritated intestines (W. B. Siegfried, S. C. Satish. Advances in the management of constipation-predominant irritable bowel syndrome: the role of linaclotide // Therapeutic Advances in Gastroenterology. 2014 Sep; 7(5): 193–205).

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News

Shipping to USA, EU, Asia, Oceania and South America in April

Notification from 1st April 2021 - Regarding shipping in Pandemic and Japan Post Stop Act. Dear Customers!   WE CAN SHIP to USA, EU, UAE, Australia, New Zealand, Canada, Hong-Kong, China, Korea, Vietnam, Mexico and all other countries!   Japan Post imposed restrictions on shipping to most of other coutnries. Situation changes eevry day, you can find latest news here - https://www.post.japanpost.jp/int/information/index_en.html Please use search on page to find your country.   IF JAPAN POST DOES NOT SHIP OR SHIPS BY SURFACE MAIL ONLY WE CAN SHIP BY COURIER.   For shiping by Japan Post check this link with full list of countries https://www.post.japanpost.jp/int/information/overview_en.html For shipping by Сourier check table below or contact us as situation changes every day.   SEE TABLE BELOW. SEE COMMENTS BELOW TABLE IF YOU CAN NOT FIND YOUR COUNTRY -- CONTACT US! W CAN SHIP. Shipping type Economy Mail ** Express Service Methods: * SURFACE AIRMAIL Courier05 *** EMS  Argentina NO YES YES YES Armenia YES  YES YES NO Australia YES  YES YES NO Austria YES  YES YES YES Azerbaijan YES  YES YES NO Belarus YES  YES YES NO Belgium YES  YES YES YES Brazil YES NO YES NO Bulgaria YES  YES YES YES Canada YES  YES YES NO Chile NO YES YES YES China YES  YES YES YES Colombia NO YES YES YES Congo YES NO YES NO Costa Rica YES NO YES NO Croatia YES  YES YES YES Cyprus NO YES YES YES Czech YES  YES YES YES Denmark YES  YES YES YES Ecuador NO NO YES NO Egypt YES YES YES NO Estonia YES  YES YES YES Finland YES  YES YES YES France YES  YES YES YES Georgia YES NO YES NO Germany YES  YES YES YES Great Britain YES  YES YES YES Greece YES  NO YES NO Hungary YES  YES YES YES India YES  NO YES NO Indonesia YES  YES YES YES Iran / Iraq NO YES  NO YES Ireland YES YES YES YES Israel YES NO YES NO Italy YES  YES YES YES Kazakhstan YES  YES NO NO Kenya NO YES YES YES Laos YES NO YES NO Latvia YES  YES YES YES Liechtenstein YES  YES YES YES Lithuania YES  YES YES YES Luxemurbg YES  YES YES YES Malaysia YES  NO YES NO Mexico YES  YES YES YES Moldova YES NO YES NO Mongolia NO NO YES NO New Zealand YES  YES YES YES Norway YES  YES YES YES Pakistan NO YES YES YES Panama NO NO YES NO Peru YES NO YES NO Poland YES  YES YES YES Portugal YES  YES YES YES Romania YES  NO YES NO Russia YES NO NO (ASK US) NO Saudi Arabia YES NO YES NO Serbia YES  YES YES NO Slovakia YES  YES YES NO Spain YES  YES YES YES Sri Lanka YES  YES YES YES Sweden YES  YES YES YES Switzerland YES  YES YES YES Tajikistan YES NO YES NO Turkey YES  YES YES YES UAE (Dubai) YES  NO YES NO Ukraine YES YES NO YES USA YES  YES* YES NO Uzbekistan YES NO YES NO Vietnam YES  YES YES YES           * We select appropriate available method. If you need specific method contact us. ** Economy mail is shipped by Air if airmail is available, if not we ship by Surface mail. There are restrictions applied by Japan Post. *** Courier-05, shipping for parcels with tablets up to 5 boxes (most cases), vials 10-20 pcs drops up to 0,5 kg in weight. Can ship to specific regions/cities, please check before order. IF YOU DO NOT SEE COUNTRY ON LIST, CONTACT US!   USA: - EXPRESS SERVICE. We ship by express, Delivery takes 8-12 days.  - AIRMAIL MAIL. If you prefer economy mail, we ship by surface mail, takes 2-4 weeks, no tracking, only local number in Japan, Rate starts at 29 usd, free shipping for orders above 400 usd and 2 kg. If you can wait use this method.   EU - EUROPE We ship as usual to all countries besides Greece, Romania, Moldova and Russia.  For Romania, Greece and Moldova: We ship using express service to all other countries in EU at the moment. Or by surface mail.   ASIA - SINGAPORE, HONG KOG, KOREA, TAIWAN, THAILAND, VIETNAM, MALAYSIA, PHILIPPINES. We ship as usual (with possible delays) to these countries   SHIPPING TO CHINA. We ship as usual by EMS or Airmail.    SHIPPING TO INDIA. - WE CAN SHIP BY COURIER. We can ship by express method almost everything. Delivery takes 8-14 days. USE EXPRESS METHOD. - WE SHIP BY SURFACE MAIL. This takes 6-8 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail.   OCEANIA - AUSTRALIA. NEW ZEALAND To Australia: - EXPRESS SERVICE. We ship by express, Delivery takes 8-12 days.  - AIRMAIL MAIL. If you prefer economy mail, we ship by surface mail, takes 2-4 weeks, no tracking, only local number in Japan, Rate starts at 29 usd, free shipping for orders above 400 usd and 2 kg. If you can wait use this method. TO NEW ZEALAND - WE SHIP AS USUAL    BRAZIL - WE CAN SHIP BY COURIER. We can ship by express method almost everything. Delivery takes 8-14 days. USE EXPRESS METHOD. - WE SHIP BY SURFACE MAIL. This takes 10-15 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail.   CANADA - EXPRESS SERVICE. We ship by express, Delivery takes 8-12 days.  - AIRMAIL MAIL. If you prefer economy mail, we ship by surface mail, takes 2-4 weeks, no tracking, only local number in Japan, Rate starts at 29 usd, free shipping for orders above 400 usd and 2 kg. If you can wait use this method.   UKRAINE, KAZAKHSTAN. RUSSIA. - WE CAN SHIP TO KAZAKHSTAN AND UKRANE as usual by  AIRMAIL WITH POSSIBLE DELAYS. EMS and courier is available for Ukraine.  - Only surface mail is allowed for Russia due to strict customs control for all other methods.
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Reviews

John

Great product, original Japanese Lactis EL027826792JP
more ▶

Reviews

Mike

Good effect. I shall order again. Original made-in-japan package as promised EG401137451JP
more ▶

Reviews

May

Real Japanese laennec. Thank you! I shall order again. EJ377189782JP
more ▶

Reviews

Bob

Great effect! Got my hair back in 3 months. EG401137588JP
more ▶

Reviews

Nike

Lost 3 kilos since started to drink it last month. Great for fitness EG299855913JP
more ▶

Reviews

Any

Bought it for my son. Good effect and great service. EG299855961JP
more ▶

Reviews

Nya

Original touchi, fast delivery and good price. Thank you. EG401137156JP
more ▶

Reviews

Sam

Good medicine. Think it really helps me to fight cancer. EL025661542JP
more ▶

Reviews

John

3 times cheaper than in our country! And great effect for knees EJ365886698JP
more ▶

Reviews

Mike

Great thing to support diet. Lost 4 kilos for 6 weeks. Shall order more EJ365886675JP
more ▶