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Digestion, Stomach, GIT

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John

Great product, original Japanese Lactis EL027826792JP
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Reviews

Mike

Good effect. I shall order again. Original made-in-japan package as promised EG401137451JP
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Reviews

May

Real Japanese laennec. Thank you! I shall order again. EJ377189782JP
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Reviews

Bob

Great effect! Got my hair back in 3 months. EG401137588JP
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Reviews

Nike

Lost 3 kilos since started to drink it last month. Great for fitness EG299855913JP
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Reviews

Any

Bought it for my son. Good effect and great service. EG299855961JP
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Reviews

Nya

Original touchi, fast delivery and good price. Thank you. EG401137156JP
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Reviews

Sam

Good medicine. Think it really helps me to fight cancer. EL025661542JP
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Reviews

John

3 times cheaper than in our country! And great effect for knees EJ365886698JP
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Reviews

Mike

Great thing to support diet. Lost 4 kilos for 6 weeks. Shall order more EJ365886675JP
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Home Japanese Supplements Digestion, Stomach, GIT
Linzess tablets 0.25 mg for constipation (Constella)
Linzess tablets 0.25 mg for constipation (Constella)
Linzess tablets 0.25 mg for constipation (Constella)
Product Code Linzess
Availability 15
Price USD 219.00
Qty
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Linzess tablets 0.25 mg for constipation (Constella)

Product Code : Linzess

Availability : 15

USD 219.00

Buy now

General information on Japanese Linzess tablets 0.25 mg for constipation     

Package details: 100 tablets

Manufacturer: Astellas Pharma Inc., Japan

Active ingredient: linaclotide (chemical formula C59H79N15O21S6)

Medical effect: Linzess tablets are effective for the treatment of the following diseases and conditions:

  • hypersensitivity in the large intestine,
  • abdominal pain and discomfort,
  • constipation-predominant irritable bowel syndrome,
  • chronic constipation.

Contraindications and precautions: do not use in pregnant or breastfeeding women. Do not use in patients who have, or are suspected of having, mechanical intestinal obstruction.

If an allergic reaction occurs, stop using the medication and consult with your doctor. If you’re taking any other medication, please consult with your doctor before use.

As this medicine is hygroscopic, take out the tablet from the sheet only just before taking the medicine. Do not leave naked unwrapped tablets or store them in a different container.

Dosage and administration of Linzess tablets 0.25 mg from Japan for constipation (Constella)

For adults, take 2 tablets 1 time a day before meals. The dosage may be reduced to 1 tablet depending on the symptoms.

The dosage may be adjusted by the consulting doctor according to age, body weight and symptoms.

How effective are Japanese Linzess tablets 0.25 mg for constipation?

Linzess tablets contain linaclotide, a synthetic tetradecapeptide mimic of endogenous guanylin and uroguanylin. It works by activating the guanylate cyclase C receptor on the surface of the intestinal epithelium. By this, Linzess tablets promote water secretion in the intestine, reduce pain by decreasing action of colonic sensory neurons and activate colonic motor neurons, which increases smooth muscle contraction. As a result, Linzess tablets from Japan effectively promote defecation.

Who should use Linzess tablets 0.25 mg from Japan (Constella)?

Linzess tablets are used for the treatment of the chronic constipation of unknown genesis and irritated bowel syndrome expressed predominantly in constipation. In general, linaclotide is a safe and effective medicine, it reduces pain and provides a physiologically sound approach to treatment of the multiple and complex symptoms of irritated intestines (W. B. Siegfried, S. C. Satish. Advances in the management of constipation-predominant irritable bowel syndrome: the role of linaclotide // Therapeutic Advances in Gastroenterology. 2014 Sep; 7(5): 193–205).

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News

Shipping to USA, EU, Asia, Oceania and South America in August

Dear Customers! Japan Post imposed restrictions on shipping to USA, EU and most of other coutnries. Situation changes eevry day, youc an find latest news here - https://www.post.japanpost.jp/int/information/index_en.html Please check this link for details on each country. https://www.post.japanpost.jp/int/information/2020/0716_01_01_en.pdf -  Updated last time on July 16th WE STILL CAN SHIP TO MOST COUNTRIES - SEE DETAILS BELOW OR CONTACT US IF YOU HAVE QUESTIONS!   USA: - EXPRESS SERVICE. We ship tablets (ketas) and supplements, eye drops (glanatec), vials to 10 pcs in total weight up to 0,5 kg per order. Delivery takes 6-10 days.  - SURFACE MAIL. We ship all other items, takes 4-6 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail.   EU - EUROPE We ship as usual (with possible delays) to the countries below (Alphabetic order):  Austria, Belgium, Bulgaria, Croatia, Czech, Denmark, Estonia, France (Monaco), Germany, Hungary, Italy, Latvia, Lithuania, Luxembourg, Netherlands (Holland), Norway, Poland, Portugal, Serbia, Slovenia, Spain, Sweden,     For other coutnries in Europe (Romania, Greece, Ukraine etc): We ship using express service to all other countries in EU at the moment. We can ship by express method for tablets and flat supplements in total weight not exceeding 0,5 kg. We ship in 7-12 business days. Delivery takes 6-10 days. USE EXPRESS METHOD. We can ship using surface mail. This takes 4-6 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail.   ASIA - SINGAPORE, HONG KOG, KOREA, TAIWAN, THAILAND, VIETNAM, MALAYSIA, PHILIPPINES. We ship as usual (with possible delays) to these countries   SHIPPING TO CHINA. We ship as usual by EMS or Surface mail.    SHIPPING TO INDIA. - WE STILL CAN SHIP TABLETS/CAPSULES. We can ship by express method for tablets and flat supplements in total weight not exceeding 0,5 kg. We ship in 7-12 business days. Delivery takes 8-14 days. USE EXPRESS METHOD. - WE SHIP BY SURFACE MAIL. This takes 4-6 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail.   OCEANIA - AUSTRALIA. NEW ZEALAND To Australia: - WE STILL CAN SHIP TABLETS/CAPSULES. We can ship by express method for tablets and flat supplements in total weight not exceeding 0,5 kg. We ship in 7-12 business days. Delivery takes 8-14 days. USE EXPRESS METHOD. - WE SHIP BY SURFACE MAIL. This takes 4-6 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail. TO NEW ZEALAND - WE SHIP AS USUAL    BRAZIL - WE STILL CAN SHIP TABLETS / CAPSULES / EYE DROPS. We can ship by express method for tablets and flat supplements in total weight not exceeding 0,5 kg. We ship in 7-12 business days. Delivery takes 8-14 days. USE EXPRESS METHOD. - WE SHIP BY SURFACE MAIL. This takes 4-6 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail.   CANADA We ship as usual with delays due to reduced number of flights.   RUSSIA, UKRAINE, KAZAKHSTAN. - WE STILL CAN SHIP TABLETS/CAPSULES. We can ship by express method for tablets and flat supplements in total weight not exceeding 0,5 kg. We ship in 7-12 business days. Delivery takes 8-14 days. USE EXPRESS METHOD. - WE SHIP BY SURFACE MAIL. This takes 4-6 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail. - WE CAN SHIP TO KAZAKHSTAN BY AIRMAIL WITH DELAYS. 
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Reviews

John

Great product, original Japanese Lactis EL027826792JP
more ▶

Reviews

Mike

Good effect. I shall order again. Original made-in-japan package as promised EG401137451JP
more ▶

Reviews

May

Real Japanese laennec. Thank you! I shall order again. EJ377189782JP
more ▶

Reviews

Bob

Great effect! Got my hair back in 3 months. EG401137588JP
more ▶

Reviews

Nike

Lost 3 kilos since started to drink it last month. Great for fitness EG299855913JP
more ▶

Reviews

Any

Bought it for my son. Good effect and great service. EG299855961JP
more ▶

Reviews

Nya

Original touchi, fast delivery and good price. Thank you. EG401137156JP
more ▶

Reviews

Sam

Good medicine. Think it really helps me to fight cancer. EL025661542JP
more ▶

Reviews

John

3 times cheaper than in our country! And great effect for knees EJ365886698JP
more ▶

Reviews

Mike

Great thing to support diet. Lost 4 kilos for 6 weeks. Shall order more EJ365886675JP
more ▶