Ebutol tablets 250 mg for tuberculosis and mycobacteriosis

General information on Japanese Ebutol tablets 250 mg for tuberculosis and mycobacteriosis

Package details: 100 tablets

Manufacturer: Kaken Pharmaceutical Co. Ltd., Japan

Active ingredient: ethambutol hydrochloride (chemical formula C10H24N2O2)

Medical effect: Ebutol tablets are effective for stopping growth of mycobacterium tuberculosis bacteria and other nontuberculous mycobacteria

Contraindications and precautions: do not use in the following categories of patients:

• patients who are known to be hypersensitive to ethambutol,
• patients with known optic neuritis,
• patients who are unable to appreciate and report visual side effects or changes in vision (e.g., young children, unconscious patients),
• patients with diabetes,
• patients with alcoholism,
• patients with kidney diseases,
• pregnant or breastfeeding women.

If you are taking any other medications, please consult with your doctor before use. While taking this medication, patients’ liver condition should be monitored regularly. If any changes in vision occur (blind spots, changes in color etc.), stop using this medication and consult with your doctor.

Dosage and administration of Japanese Ebutol tablets 250 mg for tuberculosis and mycobacteriosis

For tuberculosis: take 3-4 tablets a day, dividing into 1-2 times. A consulting doctor may decrease the dosage according to age and symptoms.

For mycobateriosis: take 2-3 tablets a day. A consulting doctor may adjust the dosage according to age and symptoms but the maximum dosage of 4 tablets a day must not be exceeded.

For the treatment of tuberculosis, Ebutol tablets are recommended to use in conjunction with other medications. The most frequently used combinations are isoniazid and isoniazid with streptomycin.

How effective are Ebutol tablets 250 mg from Japan for tuberculosis and mycobacteriosis?

Ebutol tablets’ active ingredient is ethambutol hydrochloride, a derivative of the only isomer of three existing isomers of ethambutol that has a high antituberculotic activity (S. Oka, K. Konno et al. Clinical Studies on Ethambutol. American Review of Respiratory Disease, 91(5), pp. 762–763). This substance is effective for stopping growth of Mycobacterium tuberculosis bacteria. It works by obstructing the formation of bacteria cell walls. Ebutol tablets are well absorbed from the gastrointestinal tract and well distributed in body tissues and fluids.

Who should use Ebutol tablets 250 mg from Japan?

While in some countries, like US, ethambutol hydrochloride was approved for the treatment of tuberculosis only, in Japan Ebutol tablets are also approved for the treatment of mycobacteriosis caused by non-tuberculous mycobacteria. Also, ethambutol hydrochloride is easy to combine with other antituberculotic medications like isoniazid. And for the treatment of tuberculosis, Ebuthol tablets are recommended to be taken in conjunction with other medications in order to increase their efficacy, adsorption and distribution in the body.