Benidipine hydrochloride tablets 8 mg for hypertension and angina

General information on Japanese Benidipine hydrochloride tablets 8 mg for hypertension and angina

Package details: 100 tablets

Manufacturer: Nichi-Iko Pharmaceutical Co., Ltd., Japan

Active ingredients: benidipine hydrochloride (chemical formula C28H32ClN3O6)

Medical effect: Benidipine hydrochloride tablets are effective for the treatment of hypertension, renal parenchymal hypertension and angina.

Contraindications and precautions: do not use for pregnant, possibly pregnant or breastfeeding women. Do not use for patients with cardiogenic shock.

If an allergic reaction occurs, stop taking the medicine and consult with your doctor. If you’re taking any other medication or receiving any other treatment, you have to consult with your doctor before use.

Avoid taking grapefruit juice while taking this medicine. As this medicine may cause dizziness due to decreased blood pressure, be careful when operating in potentially hazardous activities such as driving a car and working at heights.

Dosage and administration of Benidipine hydrochloride tablets 8 mg from Japan for hypertension and angina

• For hypertension and renal parenchymal hypertension: for adults, take 2-4mg of the active ingredient at a time, once a day, after breakfast. If the effect is insufficient, the consulting doctor may increase the dosage up to 1 tablet (8 mg) at a time.
• For severe hypertension: for adults, take 4-8 mg at a time, once a day, after breakfast.
• For angina: for adults, take 4 mg of the active ingredient at a time, 2 times a day, after breakfast and dinner.
• The doctor in charge may adjust the dosage according to age and symptoms of the patient.

How effective are Benidipine hydrochloride tablets 8 mg from Japan for hypertension and angina?

Benidipine hydrochloride a synthetic dihydropyridine derivative originated in Japan. It works by blocking calcium inflow into cells and consequently dilating constricted vessels to decrease blood pressure. Also, Benidipine hydrochloride tablets dilate coronary arteries of the heart to prevent developing anginal attacks. As the result, this medicine is effective for the treatment of hypertension, renal parenchymal hypertension and angina.

Who should use Benidipine hydrochloride tablets 8 mg from Japan?

Benidipine hydrochloride is a well-studied, safe and effective medicine. It has a mild onset, not resulting in changing the pulse rate. Also, studies showed that Benidipine hydrochloride tablets have a renoprotective effect, providing high usefulness in hypertensive patients with diabetes (H. Seino, S. Miyaguchi et al. “Effect of benidipine hydrochloride, a long-acting T-type calcium channel blocker, on blood pressure and renal function in hypertensive patients with diabetes mellitus”. Arzneimittelforschung, 2007; 57(8): 526-31).