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Allopurinol tablets 50 mg for hyperuricemia (gout, uric acid level)
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General information on Japanese Allopurinol tablets 50 mg for hyperuricemia (gout, uric acid level)
Package details: 100 tablets
Manufacturer: Nichi-Iko Pharmaceutical Co. Ltd. / Nisshin Pharmaceutical Co., Ltd., Japan
Active ingredients: allopurinol (chemical formula C5H4N4O)
Medical effect: Allopurinol tablets are effective for the treatment of hyperuricemia caused by gout and hypertension accompanied with hyperuricemia.
Contraindications and precautions: do not use for pregnant or breastfeeding women. Take care on the following:
- The gout attacks and pain may be temporarily intensified at the beginning of the course of treatment with Allopurinol tablets. However, the patient should not adjust the dose or stop taking the medicine without instruction of doctor or pharmacist.
- Unless the patient has heart or renal disorder, they should have plenty of water to increase urinary volume.
- If an allergic reaction occurs, the patient should stop taking the medicine and consult with your doctor.
- If a patient is taking any other medication or receiving any other treatment, they have to consult with their doctor before use.
Dosage and administration
For adults, take 4-6 tablets (200-300 mg of the active ingredient) a day, dividing into 2 to 3 doses, after meals. The doctor in charge may adjust the dosage according to disease, age and symptoms of the patients.
How effective are Allopurinol tablets 50 mg from Japan for hyperuricemia (gout, uric acid level)?
Allopurinol is an isomer of hypoxanthine, a purine naturally occurring in the body. By interfering with purine metabolism, it suppresses the production of uric acid. As allopurinol does not belong to the uricosuric group, it can be used even for patients with renal dysfunction, though the monitoring of doctor in charge is required.
Who should use Allopurinol tablets 50 mg from Japan?
Allopurinol tablets are effective for lowering the uric acid blood level. Subsequently, this medicine helps to treat hyperuricemia caused by gout and hypertension accompanied with hyperuricemia. Multiple clinical trials involving more than 4500 patients showed that Allopurinol tablets significantly increase the proportion of patients achieving a target serum urate level within 30 days (R. Seth, A. Kydd et al. “Allopurinol for chronic gout”. Cochrane Database of Systematic Reviews, 2014, 10: CD006077).