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New Year Holidays 2025 / 2026
11/12/2025
Dear Customers,
Please pay attention to work schedule and shipping delays during local New Year holidays in Japan.
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Urece tablets 2 mg for gout and hyperuricemia (dotinurad)
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Availability : 9
USD 249.00
Are Urece tablets 2 mg effective for gout and hyperuricemia (dotinurad)?
Urece tablets, containing the active ingredient dotinurad, offer a promising solution for individuals suffering from gout and hyperuricemia. The mechanism of action behind Urece tablets is quite straightforward yet effective. By inhibiting the reabsorption of uric acid in the kidneys, these tablets enhance the excretion of uric acid through urine, consequently reducing the levels of uric acid in the blood.
Dotinurad, the key component of Urece tablets, was developed in Japan and received approval for medical use in 2020. Since then, it has emerged as a pivotal treatment option for those grappling with gout and hyperuricemia. Its efficacy has been rigorously studied and validated through various clinical trials.
In a notable study titled "Efficacy of dotinurad, a selective urate reabsorption inhibitor, in patients with hyperuricemia/gout and cardiovascular risks: a pooled analysis of phase II/III studies," Japanese researchers underscored the effectiveness of dotinurad. They found that this compound not only effectively lowered serum uric acid levels in hyperuricemic patients but also demonstrated promising results for individuals with multiple cardiovascular risk factors. The significance of such findings cannot be overstated, particularly in the realm of cardiovascular health. Dotinurad's ability to address hyperuricemia while potentially mitigating cardiovascular risks opens up new avenues for patient care and management.
For individuals seeking reliable treatment options for gout and hyperuricemia, Urece tablets with dotinurad present a compelling choice. With a solid foundation in scientific research and clinical validation, these tablets offer hope and relief to those navigating the challenges of these conditions.
In conclusion, the introduction of dotinurad treatment, encapsulated in Urece tablets, marks a significant advancement in the management of gout and hyperuricemia. Its proven efficacy and mechanism of action underscore its relevance in contemporary medical practice, providing patients with a safe and effective option for addressing these conditions.
Package details: 100 tablets
Dosage and administration: For adults, begin with a starting dose of 0.5 mg of the active ingredient once daily. Adjustments to the dosage can be made based on your blood uric acid levels as necessary. Following two weeks, the dosage may be raised to 1 mg once daily, with a subsequent increase to 2 mg once daily for maintenance after six weeks. Dosage modifications should be made in accordance with your individual condition, ensuring not to exceed 4 mg once daily. Each tablet of this preparation contains 2 mg of the active ingredient. Should you experience a gout attack (pain) while using this medication, refrain from altering your dosage or discontinuing use.
Active components: Dotinurad
Therapeutic effect: treatment of gout and hyperuricemia
Contraindications and precautions: If your urine exhibits acidity, you may be prone to experiencing symptoms such as urinary stones, subsequent hematuria, and renal colic. To prevent this, it's advisable to drink plenty of water to boost urinary output and promote urine alkalinity. Do not expose to sunlight or heat. If allergic symptoms occur, discontinue use. Do not use in the following cases:
- urinary stone,
- renal dysfunction,
- liver dysfunction,
- pregnancy or breastfeeding.
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New Year Holidays 2025 / 2026
11/12/2025
Dear Customers,
Please pay attention to work schedule and shipping delays during local New Year holidays in Japan.
We stop accepting orders this year: December 25th . Please check shipping estimates on order confirmation before you pay.
We resume accepting orders next year January 7th
We stop all operations (shipping, email support) from December 27th, we shall ship all items that shall arrive by December 26th.
We resume shipping after January 7th, please wait for notifications,
Our website shall send auto-reply during holiday period. Please do not send multiple emails as there is small possibility that we may overlook them. We shall reply after the holidays, we may need 1-2 days to reply if the amount of eamils is big. Please wait.
Please pay attention to possible delays in shipping - some specific items ordered after December 10th may be only shipped after holidays. If you are in a hurry, please inquiry on shipping estimates before you pay.
There are also delays in transit that already began and shall last at least till Mid-January.
Thank you and we look forward to serving you next year. We also wish you a wonderful Holiday Season.
Sincerely yours
JHC