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New Year Holidays 2024 / 2025
03/12/2024
Please pay attention that due to local holidays in Japan (End of Year holidays – Dec 27th to Jan 5th) we shall operate as follows:
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Urece tablets 2 mg for gout and hyperuricemia (dotinurad)
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Availability : 9
USD 249.00
Are Urece tablets 2 mg effective for gout and hyperuricemia (dotinurad)?
Urece tablets, containing the active ingredient dotinurad, offer a promising solution for individuals suffering from gout and hyperuricemia. The mechanism of action behind Urece tablets is quite straightforward yet effective. By inhibiting the reabsorption of uric acid in the kidneys, these tablets enhance the excretion of uric acid through urine, consequently reducing the levels of uric acid in the blood.
Dotinurad, the key component of Urece tablets, was developed in Japan and received approval for medical use in 2020. Since then, it has emerged as a pivotal treatment option for those grappling with gout and hyperuricemia. Its efficacy has been rigorously studied and validated through various clinical trials.
In a notable study titled "Efficacy of dotinurad, a selective urate reabsorption inhibitor, in patients with hyperuricemia/gout and cardiovascular risks: a pooled analysis of phase II/III studies," Japanese researchers underscored the effectiveness of dotinurad. They found that this compound not only effectively lowered serum uric acid levels in hyperuricemic patients but also demonstrated promising results for individuals with multiple cardiovascular risk factors. The significance of such findings cannot be overstated, particularly in the realm of cardiovascular health. Dotinurad's ability to address hyperuricemia while potentially mitigating cardiovascular risks opens up new avenues for patient care and management.
For individuals seeking reliable treatment options for gout and hyperuricemia, Urece tablets with dotinurad present a compelling choice. With a solid foundation in scientific research and clinical validation, these tablets offer hope and relief to those navigating the challenges of these conditions.
In conclusion, the introduction of dotinurad treatment, encapsulated in Urece tablets, marks a significant advancement in the management of gout and hyperuricemia. Its proven efficacy and mechanism of action underscore its relevance in contemporary medical practice, providing patients with a safe and effective option for addressing these conditions.
Package details: 100 tablets
Dosage and administration: For adults, begin with a starting dose of 0.5 mg of the active ingredient once daily. Adjustments to the dosage can be made based on your blood uric acid levels as necessary. Following two weeks, the dosage may be raised to 1 mg once daily, with a subsequent increase to 2 mg once daily for maintenance after six weeks. Dosage modifications should be made in accordance with your individual condition, ensuring not to exceed 4 mg once daily. Each tablet of this preparation contains 2 mg of the active ingredient. Should you experience a gout attack (pain) while using this medication, refrain from altering your dosage or discontinuing use.
Active components: Dotinurad
Therapeutic effect: treatment of gout and hyperuricemia
Contraindications and precautions: If your urine exhibits acidity, you may be prone to experiencing symptoms such as urinary stones, subsequent hematuria, and renal colic. To prevent this, it's advisable to drink plenty of water to boost urinary output and promote urine alkalinity. Do not expose to sunlight or heat. If allergic symptoms occur, discontinue use. Do not use in the following cases:
- urinary stone,
- renal dysfunction,
- liver dysfunction,
- pregnancy or breastfeeding.
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New Year Holidays 2024 / 2025
03/12/2024
Please pay attention that due to local holidays in Japan (End of Year holidays – Dec 27th to Jan 5th) we shall operate as follows:
ORDER ACCEPTANCE
We stop accepting orders during holidays from Dec 26th to Jan 3rd. Website will not allow orders, please order on Jan 3rd, evening (Japanese time)
No suppliers will operate this week so changes in shipping time / price / product availability are possible. Product may become unavailable as well.
Please pay attention: orders paid after Dec 15th may be shipped after Jan 6th because Japan Post and courier services will not operate during Holidays. If you pay before we are 99% likely to ship before holidays. If you pay after make sure you can wait as delays are possible due to end of year holidays. Some suppliers stop working before Dec 26th, please pay attention!
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Will not work on Dec 31st , Jan 1st Jan 2nd - No email of any urgency will be replied. Thank you for understanding. Do not send sseveral emails during this period.
We shall resume support work on Jan 3rd, but we may need time to reply.
We shall continue to work as usual starting Jan 6th.
Pay attention that payments may be affected by your local holidays in your country / country of payment systems (during Christmas holidays and New Year holidays).
SHIPIPNG - DELAYS till January 10th.
We stop shipping all orders from Dec 28th to Jan 6th. Japan Post and courtier services will not work during this period so there are possible delays for some orders (mainly injections and some tablets) paid after Dec 15th
We shall resume normal work from Monday 6th.