Xarelto OD tablets 10 mg for prevention of ischemic stroke (rivaroxaban)
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General information on Japanese Xarelto OD tablets 10 mg for prevention of ischemic stroke (rivaroxaban)
Package details: 100 tablets
Manufacturer: Bayer Yakuhin, Ltd., Japan
Active ingredient: rivaroxaban (chemical formula C19H18ClN3O5S)
Medical effect: Xarelto tablets are effective for the prevent onset of ischemic stroke and systemic embolism in patients with nonvalvular atrial fibrillation.
Contraindications and precautions: do not use for the following categories of patients:
- pregnant, possibly pregnant or breastfeeding women,
- patients with bleeding (intracranial bleeding, gastrointestinal bleeding, etc.),
- patients with bleeding tendency, prolonged bleeding or high risk of bleeding,
- patients with a history of bronchiectasis or lung bleeding,
- patients with liver or renal disorder,
- patients with acute bacterial endocarditis,
- patients with low body weight,
- patients with gastric ulcer, duodenal ulcer, malignant tumor or hypertension.
If an allergic reaction occurs, stop taking the medicine and consult with your doctor. If you’re taking any other medication or receiving any other treatment, you have to consult with your doctor before use.
In case the patient is going to receive dental treatment, endoscopic examination or surgery, the doctor in charge must be informed in advance that the patient is taking this medicine.
As rivaroxaban may lead to prolonged bleeding, the patient should do their best not to get injured. If the patient gets injured and bleeding time is prolonged or the injury involves a large area, immediately contact your doctor.
Avoid taking any food or supplement containing hypericum perforatum (St. John's wort) while taking this medication.
Dosage and administration of Xarelto OD tablets 10 mg from Japan for prevention of ischemic stroke (rivaroxaban)
For adults: take 15 mg of the active ingredient at a time, once a day after meals. For patients with renal disorder, the dosage should be decreased to 10 mg at a time, once a day.
These tablets can be taken with or without water.
Please note that this medicine contains 10 mg of active ingredient in 1 tablet.
How effective are Xarelto OD tablets 10 mg from Japan for prevention of ischemic stroke (rivaroxaban)?
Each Xarelto OD tablet contains 10 mg of rivaroxaban, a factor Xa inhibitor, an anticoagulant. It works by decreasing the clotting ability of the blood and preventing harmful clots from forming in the blood vessels. Xarelto tablets allow to predict and control anticoagulation. While the dose adjustments and routine coagulation monitoring are required, this medication does not need any dietary restrictions.
Who should take Xarelto OD tablets 10 mg from Japan?
Xarelto tablets are used for the prevention of the onset of ischemic stroke and systemic embolism in patients with nonvalvular atrial fibrillation. Studies showed that using rivaroxaban, especially when combined with aspirin, reduces morbidity and mortality from coronary artery disease (S. J. Connolly, J. W. Eikelboom et al. “Rivaroxaban with or without aspirin in patients with stable coronary artery disease: an international, randomised, double-blind, placebo-controlled trial”. Lancet, 2018, January, 20; 391(10117): 205-218).