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Parkinson's Disease

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John

Great product, original Japanese Lactis EL027826792JP
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Mike

Good effect. I shall order again. Original made-in-japan package as promised EG401137451JP
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May

Real Japanese laennec. Thank you! I shall order again. EJ377189782JP
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Bob

Great effect! Got my hair back in 3 months. EG401137588JP
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Nike

Lost 3 kilos since started to drink it last month. Great for fitness EG299855913JP
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Any

Bought it for my son. Good effect and great service. EG299855961JP
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Nya

Original touchi, fast delivery and good price. Thank you. EG401137156JP
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Sam

Good medicine. Think it really helps me to fight cancer. EL025661542JP
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John

3 times cheaper than in our country! And great effect for knees EJ365886698JP
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Mike

Great thing to support diet. Lost 4 kilos for 6 weeks. Shall order more EJ365886675JP
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Home Disorders Parkinson's Disease
Trerief tablets 50 mg for Parkinson’s disease (zonisamide)
Trerief tablets 50 mg for Parkinson’s disease (zonisamide)
Product Code Trerief
Availability 12
Price USD 1,090.00
Qty
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Trerief tablets 50 mg for Parkinson’s disease (zonisamide)

Product Code : Trerief

Availability : 12

USD 1,090.00

Buy now

General information on Japanese Trerief tablets 50 mg for Parkinson’s disease (zonisamide)

Package details: 30 tablets

Manufacturer: Sumitomo Dainippon Pharma Co.,Ltd., Japan

Active ingredient: zonisamide (chemical formula C8H8N2O3S)

Medical effect: Trerief tablets are effective for the treatment of Parkinson’s disease.

Contraindications and precautions: do not use in pregnant and breastfeeding women.

As this medicine may cause drowsiness or lack of concentration, avoid working with dangerous mechanisms or driving a car while taking this medicine. If an allergic reaction occurs, stop taking the medicine and consult with your doctor. If you’re taking any other medication, please consult with your doctor before use.

Dosage and administration of Trerief tablets 50 mg from Japan for Parkinson’s disease (zonisamide)

For adults, take 0.5 tablet (25 mg of the active ingredient) once a day, concomitantly with levodopa-containing products. For improvement of circadian change of symptoms in Parkinson's disease, take 1 tablet (50 mg) once a day, concomitantly with levodopa-containing products.

The medicine can be taken with or without water. If you use it without water, moisten the tablet with saliva on the tongue and crush it lightly with the tongue, then swallow it with saliva.

How effective are Japanese Trerief tablets 50 mg for Parkinson’s disease (zonisamide)?

Trerief tablets contain zonisamide, a sulfonamide anticonvulsant and a carbonic anhydrase inhibitor. They provide the following effects:

  1. elevate the dopamine level,
  2. enhance and prolong antiparkinsonian effect of levodopa,
  3. improves motor symptoms,
  4. improve the circadian change of symptoms (wearing-off phenomenon).

Who should take Trerief tablets 50 mg from Japan?

Zonisamide was primarily used as an anticonvulsant for patient with epilepsy. Later, this medicine was found to improve the symptoms of Parkinson’s disease in patients who had both epilepsy and Parkinson’s disease. Currently, Trerief tablets have been studied in clinical trials and approved in Japan for the treatment of the motor symptoms of Parkinson's disease, as an adjunct to levodopa. Studies showed that zonisamide allows to decrease the amount of levodopa, induce quinone formation and protection against mitochondrial impairment, increase astroglial cysteine transport, inhibit the microglial activation and monoamine oxidase-B (MAO-B), increase dopamine release and block the calcium channels (N. D. Grover, R. P. Limaye et al. "Zonisamide: a review of the clinical and experimental evidence for its use in Parkinson's disease". Indian Journal of Pharmacology, 2013, 45 (6): 547–55).

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Holiday Notification

Please pay attention that there will be an Official holiday in Japan - 23rd of September. Autumnal Equinox Day.  https://en.wikipedia.org/wiki/Autumnal_Equinox_Day We shall not work on 23rd - 25th of September.  We shall resume work on Monday 26th. We shall send all payment details and reply to all inquiries on Monday. Delays in shipping are possible, we apologize for the inconvenience. JHC
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Reviews

John

Great product, original Japanese Lactis EL027826792JP
more ▶

Reviews

Mike

Good effect. I shall order again. Original made-in-japan package as promised EG401137451JP
more ▶

Reviews

May

Real Japanese laennec. Thank you! I shall order again. EJ377189782JP
more ▶

Reviews

Bob

Great effect! Got my hair back in 3 months. EG401137588JP
more ▶

Reviews

Nike

Lost 3 kilos since started to drink it last month. Great for fitness EG299855913JP
more ▶

Reviews

Any

Bought it for my son. Good effect and great service. EG299855961JP
more ▶

Reviews

Nya

Original touchi, fast delivery and good price. Thank you. EG401137156JP
more ▶

Reviews

Sam

Good medicine. Think it really helps me to fight cancer. EL025661542JP
more ▶

Reviews

John

3 times cheaper than in our country! And great effect for knees EJ365886698JP
more ▶

Reviews

Mike

Great thing to support diet. Lost 4 kilos for 6 weeks. Shall order more EJ365886675JP
more ▶