Sigmart tablets 5 mg for angina (nicorandil)

General information on Japanese Sigmart tablets 5 mg for angina (nicorandil)     

Package details: 100 tablets

Manufacturer: Chugai Pharmaceutical Co., Ltd., Japan

Active ingredient: nicorandil (chemical formula C8H9N3O4)

Medical effect: Sigmart tablets are effective for the treatment of angina and such its symptoms as chest pain and chest oppressive feeling.

Contraindications and precautions: do not use in the following categories of patients:

• patients with hepatic disorder,
• patients with glaucoma,
• pregnant women,
• breastfeeding women.

Never take sildenafil citrate (Viagra), vardenafil hydrochloride hydrate (Levitra) or tadalafil (Cialis) while taking this medication.

If an allergic reaction occurs, stop using the medication and consult with your doctor. If you’re taking any other medication, please consult with your doctor before use.

Dosage and administration of Sigmart tablets 5 mg from Japan for angina (nicorandil)

For adults, take 1 tablet at a time, 3 times a day.

The dosage may be adjusted by the consulting doctor according to age, body weight and symptoms.

How effective are Japanese Sigmart tablets 5 mg for angina (nicorandil)?

Sigmart tablets contain nicorandil, a nicotinamide ester that works as nitrate and ATP-sensitive K+ channel agonist. It is sold upon different brand names in different countries, like marketed under the trade names Ikorel, Angedil, Dancor, Nikoran, Nitorubin and others. Japanese tablets Sigmart decrease the calcium sensitivity of the smooth muscle and relax smooth muscle resulting in coronary vasodilation. This medicine helps to dilate both normal and stenotic coronary arteries.

Who should use Sigmart tablets 5 mg from Japan?

Japanese Sigmart tablets are effective for the treatment of chest pain and chest oppressive feeling by coronary dilation. They are suitable for patients with angina, including severe angina, vasospastic angina and patients with advanced coronary artery disease. Studies also showed that Sigmart tablets have a cardioprotective effect when used as part of an intervention strategy directly after acute myocardial infarction in high-risk patients (A. Markham, G. L. Plosker, K. L. Goa. “Nicorandil. An updated review of its use in ischaemic heart disease with emphasis on its cardioprotective effects”. Drugs. 2000, October, 60 (4): 955-74).