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Heart, CVS (Cardiovascular)

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John

Great product, original Japanese Lactis EL027826792JP
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Mike

Good effect. I shall order again. Original made-in-japan package as promised EG401137451JP
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May

Real Japanese laennec. Thank you! I shall order again. EJ377189782JP
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Bob

Great effect! Got my hair back in 3 months. EG401137588JP
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Nike

Lost 3 kilos since started to drink it last month. Great for fitness EG299855913JP
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Any

Bought it for my son. Good effect and great service. EG299855961JP
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Nya

Original touchi, fast delivery and good price. Thank you. EG401137156JP
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Sam

Good medicine. Think it really helps me to fight cancer. EL025661542JP
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John

3 times cheaper than in our country! And great effect for knees EJ365886698JP
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Mike

Great thing to support diet. Lost 4 kilos for 6 weeks. Shall order more EJ365886675JP
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Home Japanese Medicines Heart, CVS (Cardiovascular)
Sigmart injections 12 mg for angina (nicorandil)
Sigmart injections 12 mg for angina (nicorandil)
Product Code Sigmart inj
Availability 12
Price USD 269.00
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Sigmart injections 12 mg for angina (nicorandil)

Product Code : Sigmart inj

Availability : 12

USD 269.00

Buy now

General information on Japanese Sigmart injections 12 mg for angina (nicorandil)     

Package details: 10 vials

Manufacturer: Chugai Pharmaceutical Co., Ltd., Japan

Active ingredient: nicorandil (chemical formula C8H9N3O4)

Medical effect: Sigmart injections are effective for the treatment of the following diseases and conditions:

  • chest pain,
  • chest oppressive feeling,
  • unstable angina pectoris,
  • acute heart failure.

Contraindications and precautions: do not use in pregnant and breastfeeding women. Do not use in patients with hepatic dysfunction, renal dysfunction, cerebral dysfunction, hypotension, cardiogenic shock, Eisenmenger syndrome, primary pulmonary hypertension, right ventricular infarction, symptom of dehydration, neurocirculatory asthenia, glaucoma, left ventricular outflow tract stenosis in acute heart failure, hypertrophic obstructive cardiomyopathy or aortic valve stenosis.

Never take sildenafil citrate (Viagra), vardenafil hydrochloride hydrate (Levitra) or tadalafil (Cialis) while taking this medication.

If an allergic reaction occurs, stop using the medication and consult with your doctor. If you’re taking any other medication, please consult with your doctor before use.

Dosage and administration of Sigmart injections 12 mg from Japan for angina (nicorandil)

For angina pectoris: In general, inject with intravenous infusion.

For heart failure: In general, inject continuously and intravenously.

The treatment period with this medicine depends on the patient’s response to the treatment. The dosage may be adjusted by the consulting doctor according to age, body weight and symptoms.

How effective are Japanese Sigmart injections 12 mg for angina (nicorandil)?

Nicorandil is a nicotinamide ester working as nitrate and ATP-sensitive K+ channel agonist.Sigmart injections with nicorandil decrease the calcium sensitivity of the smooth muscle and relax smooth muscle resulting in coronary vasodilation. This medicine helps to dilate both normal and stenotic coronary arteries.

Who should use Sigmart injections 12 mg from Japan?

Sigmart injections are effective for the coronary vasodilation in patients with acute angina pectoris and for decreasing the heart burden in patients with heart failure. Studies showed that intravenous nicorandil is effective for both patients with unstable angina and variant angina, even helping with patients who are refractory to therapy with conventional antianginal agents (J. Frampton, M. M. Buckley, A. Fitton. “Nicorandil. A review of its pharmacology and therapeutic efficacy in angina pectoris”. Drugs. 1992, October, 44 (4): 625-55).

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News

Shipping to USA, EU, Asia, Oceania and South America in August

Dear Customers! Japan Post imposed restrictions on shipping to USA, EU and most of other coutnries. Situation changes eevry day. Please check this link for details on each country by Japan Post. https://www.post.japanpost.jp/int/information/overview_en.html We can ship small orders of everything besides vials to Most Countries. Please ask us on detail.  WE STILL CAN SHIP TO MOST COUNTRIES - SEE DETAILS BELOW OR CONTACT US IF YOU HAVE QUESTIONS!   USA: - EXPRESS SERVICE. We ship tablets (ketas) and supplements, eye drops (glanatec) in total weight up to 0,5 kg per order. Delivery takes 6-10 days.  - SURFACE MAIL. We ship all other items (vials), takes 7-9 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail.   EU - EUROPE We ship as usual (with possible delays) to the countries below (Alphabetic order):  Austria, Belgium, Bulgaria, Croatia, Czech, Denmark, Estonia, France (Monaco), Germany, Hungary, Italy, Latvia, Lithuania, Luxembourg, Netherlands (Holland), Norway, Poland, Portugal, Serbia, Slovenia, Spain, Sweden,     For other coutnries in Europe (Romania, Greece, Ukraine etc): We ship using express service to all other countries in EU at the moment. We can ship by express method for tablets and flat supplements in total weight not exceeding 0,5 kg. We ship in 7-12 business days. Delivery takes 6-10 days. USE EXPRESS METHOD. We can ship using surface mail. This takes 4-6 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail.   ASIA - SINGAPORE, HONG KOG, KOREA, PHILIPPINES, TAIWAN, THAILAND, VIETNAM, MALAYSIA, PHILIPPINES. We ship as usual (with possible delays) to these countries   SHIPPING TO CHINA. We ship as usual by EMS or Surface mail.    SHIPPING TO INDIA. - WE STILL CAN SHIP TABLETS/CAPSULES. We can ship by express method for tablets and flat supplements in total weight not exceeding 0,5 kg. We ship in 7-12 business days. Delivery takes 8-14 days. USE EXPRESS METHOD. - WE SHIP BY SURFACE MAIL. This takes 4-6 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail.   OCEANIA - AUSTRALIA. NEW ZEALAND To Australia: - WE STILL CAN SHIP TABLETS/CAPSULES. We can ship by express method for tablets and flat supplements in total weight not exceeding 0,5 kg. We ship in 7-12 business days. Delivery takes 8-14 days. USE EXPRESS METHOD. - WE SHIP BY SURFACE MAIL. This takes 4-6 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail. TO NEW ZEALAND - WE SHIP AS USUAL    BRAZIL - WE STILL CAN SHIP TABLETS / CAPSULES / EYE DROPS. We can ship by express method for tablets and flat supplements in total weight not exceeding 0,5 kg. We ship in 7-12 business days. Delivery takes 8-14 days. USE EXPRESS METHOD. - WE SHIP BY SURFACE MAIL. This takes 4-6 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail.   CANADA We ship as usual with delays due to reduced number of flights.   RUSSIA, UKRAINE, KAZAKHSTAN. - WE SHIP BY SURFACE MAIL. This takes 4-6 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail. - WE CAN SHIP TO KAZAKHSTAN BY AIRMAIL WITH DELAYS. 
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Reviews

John

Great product, original Japanese Lactis EL027826792JP
more ▶

Reviews

Mike

Good effect. I shall order again. Original made-in-japan package as promised EG401137451JP
more ▶

Reviews

May

Real Japanese laennec. Thank you! I shall order again. EJ377189782JP
more ▶

Reviews

Bob

Great effect! Got my hair back in 3 months. EG401137588JP
more ▶

Reviews

Nike

Lost 3 kilos since started to drink it last month. Great for fitness EG299855913JP
more ▶

Reviews

Any

Bought it for my son. Good effect and great service. EG299855961JP
more ▶

Reviews

Nya

Original touchi, fast delivery and good price. Thank you. EG401137156JP
more ▶

Reviews

Sam

Good medicine. Think it really helps me to fight cancer. EL025661542JP
more ▶

Reviews

John

3 times cheaper than in our country! And great effect for knees EJ365886698JP
more ▶

Reviews

Mike

Great thing to support diet. Lost 4 kilos for 6 weeks. Shall order more EJ365886675JP
more ▶