Recalbon tablets 1 mg for osteoporosis

General information on Japanese Recalbon tablets 1 mg for osteoporosis

Package details: 100 tablets

Manufacturer: Ono Pharmaceutical Co., Ltd., Japan

Active ingredient: minodronic acid hydrate (chemical formula C9H14N2O8P2)

Medical effect: Recalbon tablets inhibit osteoclastic bone resorption by inhibiting activity of farnesyl pyrophosphate synthase. They increase bone density and strength and prevent bone fracture.

Contraindications and precautions: recalbon tablets cannot be used for the following categories of patients:

• patients with disorder that delays esophageal transit, for example, esophageal stenosis,
• patients unable to sit upright for more than 30 minutes,
• patients with hypocalcemia,
• pregnant or breastfeeding women.

Dosage and administration of Japanese tablets Recalbon 1 mg for osteoporosis

Take 1 tablet 1 time a day with approximately 180 mL of water, strictly before the first meal or beverage of the day. At least for the first 30 minutes after taking the tablet, refrain from lying down, eating, drinking (including mineral water) or taking other medicine, except drinking usual water.

Never take this medicine after consuming any food or beverages. If you missed the dose and have already had some foods and beverages, skip the missed dose and continue regular intake from the next morning.

Do not crunch or dissolve the medicine in the mouth as it might cause irritation. Maintain your oral hygiene while taking this medicine. Do not take the medicine at bedtime or before rising. Make sure to take enough calcium and vitamin D from food or vitamin supplements.

How effective are Recalbon tablets 1 mg from Japan for osteoporosis?

Recalbon tablets contain 1 mg of bisphosphonate called minodronic acid hydrate. It inhibits activity of farnesyl pyrophosphate synthase, thus, inhibiting osteoclastic bone resorption. Its action is 1000 times more effective than etidronic acid and 10 to 100 times more effective than alendronic acid. Recalbon tablets effectively prevent new vertebral and nonvertebral fractures.

Who should use Recalbon tablets 1 mg for osteoporosis?

Japanese tablets Recalbon 1 mg for osteoporosis are effective for both primary and secondary osteoporosis. Studies show that minodronic acid hydrate is effective for increasing bone density and strength in patients with osteoporosis of different aetiology, like postmenopausal osteoporosis or steroid-induced osteoporosis (for example, see N. Kitamura, S. Shiraiwa et al.  Efficacy and safety of minodronic acid hydrate in patients with steroid-induced osteoporosis. International journal of rheumatic diseases, 2018 Apr, 21(4):813-820).