Metoprolol tartrate tablets 20 mg for hypertension, angina pectoris and tachyarrhythmia (Lopressor, Seloken, Metolar)

General information on Japanese Metoprolol tartrate tablets 20 mg for essential hypertension, angina pectoris and tachyarrhythmia (Lopressor, Seloken, Metolar)

Package details: 100 tablets

Manufacturer: Sawai Pharmaceutical Co., Ltd. / Towa Pharmaceutical Co., Ltd. / Sun Pharma Japan Limited, Japan

Active ingredients: metoprolol tartrate (chemical formula C34H56N2O12)

Medical effect: Metoprolol tartrate tablets are effective for the treatment of essential hypertension, angina pectoris and tachyarrhythmia.

Contraindications and precautions: do not use for pregnant, possibly pregnant or breastfeeding women. Do not use for patients with diabetic ketoacidosis, metabolic acidosis, bradycardia, atrioventricular block, sinoatrial block, sick sinus syndrome, cardiogenic shock, right heart failure due to pulmonary hypertension, congestive heart failure, hypotension, asthma, peripheral circulation disorder or untreated pheochromocytoma. Do not use for patients waiting to undergo surgery.

If an allergic reaction occurs, stop taking the medicine and consult with your doctor. If you’re taking any other medication or receiving any other treatment, you have to consult with your doctor before use.

As this medicine may provoke the sudden dizziness, the patient should take care when working at heights, operating dangerous machinery, or driving a car.

Dosage and administration

For essential hypertension (mild to moderate): for adults, take 1-2 tablets (20-40 mg of the active ingredient) at a time, 3 times a day. If the effect is insufficient, the dosage may be increased up to 12 tablets (240 mg) a day.

For angina pectoris, tachyarrhythmia: for adults, take 3-6 tablets (60-120 mg) a day, dividing into 2 or 3 doses.

The doctor in charge may adjust the dosage according to patient’s disease, age or symptoms.

How effective are Metoprolol tartrate tablets 20 mg from Japan for essential hypertension, angina pectoris and tachyarrhythmia (Lopressor, Seloken, Metolar)?

Metoprolol is a selective β1 receptor blocker. It lowers the pulse rate, controls irregular pulse and decreases the blood pressure. This medicine features the following properties:

• A tartrate is the immediate-release version of metoprolol while a succinate has an extended release,
• Metoprolol tartrate tablets, unlike the succinate forms, suppress the excess activity of the heart, preventing angina attacks,
• This medicine prevents further heart problems after myocardial infarction and prevents headaches in patients with migraines.

Studies showed that metoprolol tartrate provides significant improvement in quality of life, ejection fraction, exercise capacity and decreases the need for heart transplantation (W. E. Chavey II. “The Importance of Beta Blockers in the Treatment of Heart Failure”. American Family Physician, 2000, 62(11): 2453-2462).

Who should use Metoprolol tartrate tablets 20 mg from Japan?

Metoprolol tartrate tablets are prescribed for the treatment of essential hypertension, angina pectoris and tachyarrhythmia. There are also evidences that metoprolol helps to treat performance anxiety and social phobias by suppressing such reactions to stress as sweating, dizziness, and rapid heart rate.