Medrol tablets 4 mg for inflammation and allergy (methylprednisolone, glucocorticoid, steroid hormone therapy)

General information on Japanese Medrol tablets 4 mg for inflammation and allergy (methylprednisolone, glucocorticoid, steroid hormone therapy)

Package details: 100 tablets

Manufacturer: Pfizer Japan Inc.., Japan

Active ingredient: methylprednisolone (chemical formula C22H30O5)

Medical effect: Medrol tablets are effective for the treatment of the inflammations and allergic symptoms including following:

• asthma,
• seasonal or perennial allergic rhinitis,
• drug hypersensitivity reactions,
• dermatitis, including atopic, contact, severe seborrheic and exfoliative dermatitis,
• psoriasis,
• primary or secondary adrenocortical insufficiency,
• inflammatory bowel disease and ulcerative colitis,
• systemic lupus erythematosus,
• rheumatoid arthritis etc.

Contraindications and precautions: do not use for pregnant or breastfeeding women. Do not use for patients with infections, mycosis, peptic ulcer, diverticulitis, mental disease, tuberculous disease, herpes simplex keratitis, posterior subcapsular cataract, glaucoma, hypertension, electrolyte abnormality, thrombosis, a surgery of internal organs recently or a history of acute myocardial infarction.

Pay attention to avoid stress such as vigorous exercise. Pay attention not to have measles or chicken pox. If you are to receive a live vaccine or live attenuated vaccine, be sure to consult with your doctor first.

If an allergic reaction occurs, stop taking the medicine and consult with your doctor. If you’re taking any other medication, please consult with your doctor before use.

Dosage and administration of Medrol tablets 4 mg from Japan for inflammation and allergy (methylprednisolone, glucocorticoid, steroid hormone therapy)

For adults: take 1-12 tablets (4-48 mg of the active ingredient) in 1-4 divided doses per day. The doctor in charge may adjust the dosage according to the age or symptoms.

For children: the dosage should be calculated by the pediatrician in charge according to the age or symptoms.

How effective are Medrol tablets 4 mg from Japan for inflammation and allergy (methylprednisolone, glucocorticoid, steroid hormone therapy)?

Medrol tablets contain methylprednisolone, a synthetic glucocorticoid having a similar action to adrenocortical hormone produced within the body. It has a higher affinity to glucocorticoid receptors than other exogenous glucocorticoids which tend to affect the mineralocorticoid receptors more. Medrol tablets regulate the number and function of leukocytes, cytokines and chemokines and, by this and by dampening signal transduction downstream of pattern recognition receptors, effectively suppress inflammatory and immune responses (D. W. Cain, J. A. Cidlowski. "Immune regulation by glucocorticoids". Nature Reviews. Immunology. 2017, April, 17 (4): 233–247).

Who should take Medrol tablets 4 mg from Japan?

Medrol tablets are effective for the treatment of various diseases and conditions, including asthma, seasonal or perennial allergic rhinitis, drug hypersensitivity reactions, atopic, contact, severe seborrheic and exfoliative dermatitis, psoriasis, primary or secondary adrenocortical insufficiency, inflammatory bowel disease and ulcerative colitis, systemic lupus erythematosus, rheumatoid arthritis and many others. This medicine can be used by both adults and children. However, for pediatric patients the dosage should be calculated individually by the doctor in charge.