Loratadine OD tablets 10 mg for allergy (Claritin, antihistamine)

General information on Japanese Loratadine OD tablets 10 mg for allergy (Claritin, antihistamine)

Package details: 100 tablets

Manufacturer: Sawai Pharmaceutical Co., Ltd. / Nipro Pharma Corporation, Japan

Active ingredients: loratadine (chemical formula C22H23ClN2O2)

Medical effect: Loratadine tablets are effective for the treatment of the following diseases and conditions:

• allergic rhinitis is the main indication for use of Loratadine OD tablets, alleviating both nasal and eye symptoms,
• urticaria,
• eczema and dermatitis,
• pruritis and other itching associated with skin diseases.

Contraindications and precautions: do not use for pregnant or breastfeeding women.

If an allergic reaction occurs, stop taking the medicine and consult with your doctor. If you’re taking any other medication or receiving any other treatment, you have to consult with your doctor before use.

Dosage and administration

For adults: take 1 tablet (10 mg of the active ingredient) at a time, once a day after meal. The doctor in charge may adjust the dosage according to the disease, age or symptoms.

For children of 7 years old or more: take 1 tablet at a time, once a day, after meal.

This medicine may be taken with or without water. When taken without water, it should be moistened with saliva on the tongue, then lightly squashed with the tongue, and swallowed with saliva. However, patient should not take it without water while lying on back.

How effective are Loratadine OD tablets 10 mg from Japan for allergy (Claritin, antihistamine)?

Loratadine is an anti-inflammatory medicine and a tricyclic antihistamine, working as a selective inverse agonist of peripheral histamine H1 receptors. It binds to plasma proteins up to 99% and has a rapid first-pass hepatic metabolism.

Who should use Loratadine OD tablets 10 mg from Japan?

Loratadine OD tablets are effective for the treatment of allergic rhinitis, urticaria and itching associated with skin diseases, including eczema, dermatitis and pruritis. They can be used for adults and children over 7 years old. Studies showed that due to small amount of loratadine crossing the blood-brain barrier, it provides significantly less of such effects as drowsiness, altered mood, reduced wakefulness, and impaired cognitive and psychomotor performance than the first-generation antihistamines, making it famous as non-sedative antihistamine (G. G. Kay, A. G. Harris. “Loratadine: a non-sedating antihistamine. Review of its effects on cognition, psychomotor performance, mood and sedation”. Clinical & Experimental Allergy, 1999, 29 Suppl 3:147-50).