Gasmotin tablets 5 mg for gastritis (mosapride)

General information on Japanese Gasmotin tablets 5 mg for gastritis (mosapride)

Package details: 100 tablets

Manufacturer: Sumitomo Dainippon Pharma Co., Ltd., Japan

Active ingredient: mosapride citrate hydrate (chemical formula     

C21H25ClFN3O3. C6H8O7. 2H2O)

Medical effect: Gasmotin tablets are effective for the treatment of heartburn, nausea and vomiting caused by chronic gastritis and adjunctive treatment to the pretreatment with orally gastrointestinal lavage solution for barium enema X-ray examination.

Contraindications and precautions: do not use for pregnant and breastfeeding women.

If an allergic reaction occurs, stop taking the medicine and consult with your doctor. If you’re taking any other medication, please consult with your doctor before use.

Dosage and administration

1. For the treatment of heartburn, nausea and vomiting associated with chronic gastritis: for adults, take 1 tablet (5 mg of active ingredient), 3 times a day, before or after meal.
2. For the adjunctive treatment to the pretreatment with orally gastrointestinal lavage solution for barium enema X-ray examination: for adults, take 4 tablets (20 mg of active ingredient) with the orally gastrointestinal lavage solution (approximately 180 ml) at the time of administration of the lavage solution, and take 4 tablets with a small amount of water after administration of the lavage solution.

How effective are Gasmotin tablets 5 mg from Japan for gastritis (mosapride)?

Gasmotin tablets contain mosapride, a gastroprokinetic agent and a selective 5-hydroxytryptamine receptor 4 agonist. It works by stimulating serotonin receptor in the digestive tract and increasing acetylcholine release. By this, Gasmotin tablets improve functions of enterokinesis and gastric emptying.

Who should take Gasmotin tablets 5 mg from Japan?

Gasmotin tablets are effective for the treatment of heartburn, nausea and vomiting caused by chronic gastritis and adjunctive treatment to the pretreatment with orally gastrointestinal lavage solution for barium enema X-ray examination. Studies showed that mosapride enhances gastrointestinal motility by increasing the frequency or strength of contractions, exerts anti-inflammatory effects on the gastrointestinal tract and promotes neurogenesis in the gastrointestinal tract (Y. Tsuchida, F. Hatao et al. “Neuronal stimulation with 5-hydroxytryptamine 4 receptor induces anti-inflammatory actions via α7nACh receptors on muscularis macrophages associated with postoperative ileus”. Gut, 2011, 60: 638-647).