Acarbose tablets 50 mg for hyperglycemia (Glucobay, Precose, Prandase)
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General information on Japanese Acarbose tablets 50 mg for hyperglycemia (Glucobay, Precose, Prandase)
Package details: 100 tablets
Manufacturer: Pfzer Japan Inc., Japan
Active ingredient: acarbose (chemical formula C25H43NO18)
Medical effect: Acarbose tablets are effective for decreasing postprandial hyperglycemia and reducing blood sugar level.
Contraindications and precautions: do not use for pregnant and breastfeeding women. Do not use for patients with ketosis, diabetic coma or precoma, infection, before or after surgery condition, trauma, history of laparotomy or intestinal obstruction, liver or renal disorder, gastrointestinal disorder.
If you feel the symptoms of hypoglycemia (cold and sweating, arms and legs trembling etc.), take 5-10 g of glucose. As the decreased blood sugar may cause dizziness, avoid driving a car or operating dangerous mechanisms while taking this medicine.
If an allergic reaction occurs, stop taking the medicine and consult with your doctor. If you’re taking any other medication, please consult with your doctor before use.
Dosage and administration of Acarbose tablets 50 mg from Japan for hyperglycemia (Glucobay, Precose, Prandase)
In general, for adults, take 2 tablets (100 mg of active ingredient) 3 times a day before meal. It’s better to start from taking 1 tablet (50 mg of active ingredient) at once and then gradually increase the dosage, monitoring the body’s response. The dosage can be adjusted by the consulting doctor according to age and symptoms.
How effective are Acarbose tablets 50 mg from Japan for hyperglycemia (Glucobay, Precose, Prandase)?
Acarbose is a starch blocker that works by inhibiting enzymes such as glucoamylase present in the microvilli of the small intestinal mucosa. Also, this medicine inhibits α-amylase in pancreatic juice and saliva. By this, Acarbose tablets provide the following effects:
- suppress a rapid rise in blood glucose after meals,
- reduce the rate of digestion of complex carbohydrates,
- decrease blood glucose levels,
- decrease glycated hemoglobin level.
Who should take Acarbose tablets 50 mg from Japan?
Acarbose tablets are effective for preventing the hyperglycemia after meal in patients with diabetes mellitus type 2 and prediabetes. Studies showed that this medicine is significantly more effective in patients eating a relatively high carbohydrate diet (Q. Zhu, Y. Tong et al. "Comparison of the hypoglycemic effect of acarbose monotherapy in patients with type 2 diabetes mellitus consuming an Eastern or Western diet: a systematic meta-analysis". Clinical Therapeutics. 2013, June, 35 (6): 880–99). However, since acarbose is excreted through renal system, it is not suitable for patients with renal disorders.