General information on Japanese Zolmitriptan OD Tablets 2.5 mg for treatment of migraine attacks (triptan, headache, Zomig)
Package details: 12 tablets
Manufacturer: Nichi-Iko Pharmaceutical Co., Ltd., Nihon Generic Co., Ltd., Towa Pharmaceutical Co., Ltd., Japan
Active ingredient: zolmitriptan
Medical effect: Zolmitriptan tablets are effective for the treatment of migarine attacks.
Contraindications and precautions: do not use for pregnant and breastfeeding women. Do not administer to individuals with a prior history of heart attack, stroke, or transient cerebral ischemic episodes. Additionally, refrain from using this medication in patients with ischemic heart disease or any associated symptoms, variant angina (coronary vasospasm), peripheral vascular disorders, or hypertension.
If you experience no relief after the initial dose, refrain from increasing the dosage. Instead, discontinue use and consult your healthcare provider.
This medication is not intended for migraine prevention; it should only be used at the onset of a migraine attack.
Due to the potential for drowsiness, patients are advised to avoid activities such as driving, operating heavy machinery, or working at elevated heights while taking this medication.
If an allergic reaction occurs, stop taking the medicine and consult with your doctor. If you’re taking any other medication, please consult with your doctor before use.
Dosage and administration
For adults, it is recommended to take one tablet containing 2.5 mg of the active ingredient after the onset of a migraine attack. If an additional dose is required, ensure that at least 2 hours have passed since the last dose. Your physician may consider increasing the dosage to two tablets, totaling 5 mg, for future migraine attacks. Nevertheless, the maximum daily dosage of four tablets, equivalent to 10 mg, should never be exceeded under any circumstances.
This medication can be taken with or without water. If you opt to take it without water, first moisten the tablet with saliva on your tongue, gently press it with your tongue, and then swallow it with saliva.
It is important to note that this medication should only be used after the onset of a migraine headache. It should not be taken as a preventive measure for migraines.
How effective are Zolmitriptan OD Tablets 2.5 mg for treatment of migraine attacks (triptan, headache, Zomig)?
Zolmitriptan OD tablets are a prescribed medication designed to address migraine attacks. These tablets fall under the category of triptans, a specialized class of pharmaceuticals tailored for managing migraines. Their primary mode of action involves narrowing blood vessels and regulating pain signaling pathways within the brain.
Zolmitriptan exerts its effects by attaching to serotonin (5-HT1B/1D) receptors situated on blood vessels in the brain. Activation of these receptors triggers vasoconstriction, which reduces the expansion of cranial arteries, a key characteristic of migraine attacks. This constriction subsequently curtails the release of inflammatory neuropeptides and the transmission of pain signals, thereby relieving the headache associated with migraines.
Who should take Zolmitriptan tablets from Japan?
The orally disintegrating version of Zolmitriptan is particularly beneficial for individuals who may encounter nausea and have difficulty swallowing during migraine attacks. This formulation swiftly dissolves in the mouth, allowing for rapid absorption through the oral mucosa, facilitating quicker relief.
Clinical studies have demonstrated the effectiveness of Zolmitriptan OD tablets in treating migraines. When taken at the onset of a migraine attack, Zolmitriptan has been shown to alleviate migraine-related symptoms in a significant percentage of patients, including following:
sensitivity to light (photophobia),
sensitivity to sound (phonophobia),
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