Trobicin injections for bacterial infections (antibiotic, spectinomycin)

General information on Japanese Trobicin injections for bacterial infections (antibiotic, spectinomycin)

Package details: 5 powder vials * 2 g (solution ampoules included)

Manufacturer: Pfizer Japan Inc., Japan

Active ingredients: spectinomycin hydrochloride (chemical formula C14H25ClN2O7)

Medical effect: Trobicin injections are effective for the treatment of bacterial infections

Contraindications and precautions: do not use for the following categories of patients:

• children,
• pregnant or breastfeeding women,
• patients with syphilis,
• patients with atopic dermatitis.

Patients with gonorrhea treated with this medicine should have additional tests for syphilis. Use with caution for elderly patients.

If an allergic reaction occurs, stop using the medicine and consult with your doctor. If you’re taking any other medication or receiving any other treatment, you have to consult with your doctor before use.

Dosage and administration

For adults: reconstitute 1 powder vial with 3.2 mL of sterile water for injection, shake vials vigorously after mixing. Make an intramuscular injection deep into the upper outer quadrant of the gluteal muscle. Do not make an injection in exactly the same place as the previous one. A 20-gauge needle is recommended.

Use one powder vial (2 g of active ingredient) at a time. However, if the effect is insufficient or the region is known for a high antibiotic-resistance rate, a doctor in charge may increase the dosage up to 2 vials (4 g of active ingredient) at a time. In this case, it’s recommended to use 2 separate solutions and to inject them in the right and left gluteal muscles accordingly.

How effective are Trobicin injections from Japan for bacterial infections (antibiotic, spectinomycin)?

Trobicin injections contain spectinomycin, a pyranobenzodioxin and an aminocyclitol antibiotic. It works by binding to the subunit of the bacterial ribosome and interrupting protein synthesis of bacteria. Studies showed that spectinomycin can be used for patients who are allergic to penicillin or cephalosporins (W. J. Holloway. Spectinomycin // The Medical clinics of North America. 1982, 66(1):169-73).

Who should use Trobicin injections from Japan?

Trobicin injections are effective for the treatment of bacterial infections caused by gram-negative bacteria, especially for gonorrhea. This medicine is recommended for use in treatment of acute gonorrheal urethritis and proctitis in the male and acute gonorrheal cervicitis and proctitis in the female caused by susceptible strains of Neisseria gonorrhoeae.