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Good effect. I shall order again. Original made-in-japan package as promised EG401137451JP
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Real Japanese laennec. Thank you! I shall order again. EJ377189782JP
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Lost 3 kilos since started to drink it last month. Great for fitness EG299855913JP
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Bought it for my son. Good effect and great service. EG299855961JP
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Tacrolimus tablets 1 mg for transplantation (FK-506, Fujimycin, Graceptor, Advagraf)
Tacrolimus tablets 1 mg for transplantation (FK-506, Fujimycin, Graceptor, Advagraf)
Tacrolimus tablets 1 mg for transplantation (FK-506, Fujimycin, Graceptor, Advagraf)
Product Code Tacrolimus
Availability 7
Price USD 790.00
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Tacrolimus tablets 1 mg for transplantation (FK-506, Fujimycin, Graceptor, Advagraf)

Product Code : Tacrolimus

Availability : 7

USD 790.00

Buy now

General information on Japanese Tacrolimus tablets 1 mg for transplantation (FK-506, Fujimycin, Graceptor, Advagraf)

Package details: 100 tablets

Manufacturer: Towa Pharmaceutical Co., Ltd., Japan

Active ingredients: tacrolimus hydrate (chemical formula C44H71NO13)

Medical effect: Tacrolimus tablets are effective for the suppression of organ transplant rejection and graft-versus-host reaction.

Contraindications and precautions: do not use for pregnant, possibly pregnant or breastfeeding women. Do not use in patients with liver disorder, renal disorder, or infections.

Avoid drinking grapefruit juice or taking any food or supplement containing Hypericum perforatum (St. John's wort) while taking this medicine. Do not receive vaccination without an approval of your doctor while taking this medicine.

Since the possibility to become infected increases, the patient should wash hands, gargle and regulate their daily life.

If an allergic reaction occurs, stop taking the medicine and consult with your doctor. If you’re taking any other medication or receiving any other treatment, you have to consult with your doctor before use.

Dosage and administration of Tacrolimus tablets 1 mg from Japan for transplantation (FK-506, Fujimycin, Graceptor, Advagraf)

The dosage schedule should be prescribed by doctor in charge. The general regulations are the following:

  • For renal transplantation: take 0.15 mg/kg of tacrolimus at a time, 2 times a day from 2 days before transplantation. In the early stage after operation, take 0.15 mg/kg 2 times a day. Subsequently, the dosage should be gradually decreased. The standard maintenance dose is 0.06 mg/kg 2 times a day, but the doctor in charge may adjust the dosage according to the patient's symptoms.
  • For liver transplantation: initially take 0.15 mg/kg at a time 2 times a day. Subsequently, the dosage should be gradually decreased. The standard maintenance dose is 0.10 mg/kg daily, but the doctor in charge may adjust the dosage according to the patient's symptoms.
  • For heart transplantation: initially take 0.03-0.15 mg/kg at a time 2 times a day. When tacrolimus is used after development of organ rejection, take 0.075-0.15 mg/kg 2 times a day. Subsequently, the doctor in charge may adjust the dosage according to the patient's symptoms. After stable condition is achieved, the dosage should be gradually decreased and maintained at the minimal effective dose.
  • For lung transplantation: initially take 0.05-0.15 mg/kg at a time 2 times a day. Subsequently, the doctor in charge may adjust the dosage according to the patient's symptoms. After stable condition is achieved, the dosage should be gradually decreased and maintained at the minimal effective dose.
  • For pancreas transplantation: initially take 0.15 mg/kg at a time 2 times a day. Subsequently, the dosage should be gradually decreased and maintained at the minimal effective dose.
  • For small intestine transplantation: initially take 0.15 mg/kg at a time 2 times a day. Subsequently, the dosage should be gradually decreased and maintained at the minimal effective dose.
  • For bone marrow transplantation: take 0.06 mg/kg at a time 2 times a day from 1 day before transplantation. In the early stage of transplantation, take 0.06 mg/kg 2 times a day, then it should be gradually decreased. When used after the development of graft-versus-host reaction, take 0.15 mg/kg 2 times a day. The doctor in charge may adjust the dosage according to the patient's symptoms.

Please note that this preparation contains 1 mg of the active ingredient in one tablet.

How effective are Tacrolimus tablets 1 mg from Japan for transplantation (FK-506, Fujimycin, Graceptor, Advagraf)?

Tacrolimus hydrate is a macrolide with various functions. It was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. It works by binding to the immunophilin and inhibiting T-lymphocyte signal transduction.

Who should use Tacrolimus tablets 1 mg from Japan?

Tacrolimus tablets are effective for the suppression of organ transplant rejection (kidney, liver, heart, lung, pancreas, small intestine, bone marrow) or graft-versus-host reaction (bone-marrow transplantation only). They inhibit the production of cytokines associated with organ transplant rejection, and thus suppress the refusal response. Studies showed that use of tacrolimus significantly reduced the risks after liver transplantation of death, graft loss, acute rejection and steroid-resistant rejection (V. C. McAlister, E. Haddad et al. “Cyclosporin versus Tacrolimus as Primary Immunosuppressant After Liver Transplantation: A Meta-Analysis”. American Journal of Transplantation, 2006, 6(7): 1578-85).

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News

New Year Holidays 2021/2022

Please pay attention that due to local holidays in Japan (End of Year holidays – Dec 25th to Jan 5th) we shall operate as follows:   ORDER ACCEPTANCE   We stop accepting orders during holidays from Dec 25th to Jan 3rd. No suppliers will operate this week so changes in shipping time / price / product availability are possible,   Please pay attention: orders paid after Dec 12th may be shipped after Jan 4th because Japan Post and courier services will not operate during Holidays. If you pay before we are 99% likely to ship before holidays. If you pay after make sure you can wait as delays are possible due to end of year holidays. Some suppliers stop working earlier so we warn in advance.   SUPPORT TEAM and PAYMENT CONFIRMATIONS   Will not work on Dec 31st and Jan 1st. No email of any urgency will be replied. Thank you for understanding. We shall resume support work on Jan 2nd, but we may need time to reply. We shall continue to work as usual after Jan 5th. Pay attention that payments may be affected by your local holidays.   SHIPIPNG   We stop shipping all orders from Dec 29th to Jan 5th. Japan Post and courtier services will not work during this period so there are possible delays for some orders paid after Dec 12th.
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Reviews

John

Great product, original Japanese Lactis EL027826792JP
more ▶

Reviews

Mike

Good effect. I shall order again. Original made-in-japan package as promised EG401137451JP
more ▶

Reviews

May

Real Japanese laennec. Thank you! I shall order again. EJ377189782JP
more ▶

Reviews

Bob

Great effect! Got my hair back in 3 months. EG401137588JP
more ▶

Reviews

Nike

Lost 3 kilos since started to drink it last month. Great for fitness EG299855913JP
more ▶

Reviews

Any

Bought it for my son. Good effect and great service. EG299855961JP
more ▶

Reviews

Nya

Original touchi, fast delivery and good price. Thank you. EG401137156JP
more ▶

Reviews

Sam

Good medicine. Think it really helps me to fight cancer. EL025661542JP
more ▶

Reviews

John

3 times cheaper than in our country! And great effect for knees EJ365886698JP
more ▶

Reviews

Mike

Great thing to support diet. Lost 4 kilos for 6 weeks. Shall order more EJ365886675JP
more ▶