Rilmazafone hydrochloride tablets 2 mg for insomnia (RHYTHMY)

General information on Japanese Rilmazafone hydrochloride tablets 2 mg RHYTHMY for insomnia     

Package details: 100 tablets

Manufacturer: KYOWA PHARMACEUTICAL INDUSTRY CO., LTD., Japan

Active ingredient: rilmazafone hydrochloride (chemical formula C21H25Cl3N6O5)

Medical effect: Rilmazafone hydrochloride tablets are effective for the treatment of insomnia and as pre-anesthetic medication.

Contraindications and precautions: do not use in the following categories of patients:

• pregnant or breastfeeding women,
• patients with glaucoma or myasthenia gravis,
• patients with the diseases of the lung or respiratory system,
• debilitated patients,
• patients with heart, liver, renal or brain disorder.

If an allergic reaction occurs, stop using the medication and consult with your doctor. If you’re taking any other medication, please consult with your doctor before use.

As this medicine may cause sleepiness, avoid driving a car, working at heights or operating dangerous machinery. Avoid drinking alcohol or taking caffeine (tea or coffee) while taking this medication.

Dosage and administration of Rilmazafone hydrochloride tablets 2 mg from Japan for insomnia

For insomnia: for adults, take 0.5 to 1 tablet at a time, once a day before bedtime.

For pre-anesthetic effect: for adults, take 1 tablet at a time, before bedtime or before surgery.

The dosage may be adjusted by the consulting doctor according to age, weight and symptoms.

How effective are Japanese Rilmazafone hydrochloride tablets 2 mg for insomnia?

Rilmazafone hydrochloride is a water-soluble benzodiazepine prodrug developed in Japan. It works by enhancing the effects of GABA, an inhibitory transmitter in the central nervous system. By this, rilmazafone helps to relieve anxiety and tension and induce sleep.

Who should take Rilmazafone hydrochloride tablets 2 mg from Japan?

Rilmazafone is an effective hypnotic that helps to induce sleep. It is generally well tolerated and has no serious side effects. Japanese researches particularly recommend using rilmazafone for the elderly with early morning awakening as it doesn’t have any next-day residual effects (S. Uemura, T. Kanbayashi et al. “Residual effects of zolpidem, triazolam, rilmazafone and placebo in healthy elderly subjects: A randomized double-blind study”. Sleep Medicine. 2015, 16 (11), pp. 1395-1402).