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John

Great product, original Japanese Lactis EL027826792JP
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Mike

Good effect. I shall order again. Original made-in-japan package as promised EG401137451JP
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May

Real Japanese laennec. Thank you! I shall order again. EJ377189782JP
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Bob

Great effect! Got my hair back in 3 months. EG401137588JP
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Nike

Lost 3 kilos since started to drink it last month. Great for fitness EG299855913JP
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Any

Bought it for my son. Good effect and great service. EG299855961JP
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Nya

Original touchi, fast delivery and good price. Thank you. EG401137156JP
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Sam

Good medicine. Think it really helps me to fight cancer. EL025661542JP
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John

3 times cheaper than in our country! And great effect for knees EJ365886698JP
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Great thing to support diet. Lost 4 kilos for 6 weeks. Shall order more EJ365886675JP
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Rapalimus gel 0.2% for skin lesions in tuberous sclerosis (sirolimus, rapamycin)
Rapalimus gel 0.2% for skin lesions in tuberous sclerosis (sirolimus, rapamycin)
Rapalimus gel 0.2% for skin lesions in tuberous sclerosis (sirolimus, rapamycin)
Product Code Rapalimus gel
Availability 5
Price USD 990.00
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Rapalimus gel 0.2% for skin lesions in tuberous sclerosis (sirolimus, rapamycin)

Product Code : Rapalimus gel

Availability : 5

USD 990.00

Buy now

General information on Japanese Rapalimus gel 0.2% for skin lesions in tuberous sclerosis (sirolimus, rapamycin)

Package details: 1 tube * 10 g

Manufacturer: Nobelpharma Co., Ltd., Japan

Active ingredients: sirolimus (chemical formula C51H79NO13)

Medical effect: Rapalimus gel is effective for the treatment of skin erosions associated with tuberous sclerosis complex.

Contraindications and precautions: do not use for pregnant or breastfeeding women.

Do not use on mucous membrane. When applying around eyes, take care not to get the medicine into your eyes. Do not apply on the injured areas.

If the area of application is exposed to sunlight or ultraviolet rays, allergy-like symptoms may occur. Patient should take measures such as applying sunscreen on and around the application area.

After opening, store in a refrigerator at 2-8 degrees Celsius. Do not freeze.

If an allergic reaction occurs, stop using the medicine and consult with your doctor. If you’re taking any other medication or receiving any other treatment, you have to consult with your doctor before use.

Dosage and administration

Apply an appropriate amount to the affected area 2 times a day. In general, the maximum single dose is 0.2 g (approx. 0.5 cm) for 5 years old or younger, 0.3 g (approx. 0.75 cm) for 6 to 11 years old, and 0.4 g (approx. 1 cm) for 12 years old or older.

How effective are Rapalimus gel 0.2% from Japan for skin lesions in tuberous sclerosis (sirolimus, rapamycin)?

Rapalimus gel contains sirolimus, also called rapamycin, a macrolide compound produced the bacterium Streptomyces hygroscopicus. It works by inhibiting a protein kinase called mTOR (mechanistic target of rapamycin) which is activated in patients with tuberous sclerosis complex. As the result, Rapalimus gel suppresses excessive cell proliferation and improves the skin lesions.

Who should use Rapalimus gel 0.2% from Japan?

Rapalimus gel is effective for the treatment of skin lesions associated with tuberous sclerosis complex. Studies of Japanese scientists showed that topical gel with sirolimus is safe and well-tolerated even in long-term (from 52 to 136 weeks) use (M. Wataya-Kaneda, H. Nagai et al. “Safety and Efficacy of the Sirolimus Gel for TSC Patients With Facial Skin Lesions in a Long-Term, Open-Label, Extension, Uncontrolled Clinical Trial”. Dermatology and Therapy, 2020, 10(4): 635–650).

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ATTENTION! Website Maintenance 8/11 - 8/12

Website Maintenance will take place during August 11th - 12th, Acceptance of ALL ORDERS will be suspended for TWO DAYS. We stop accepting orders for 48 hours from AUGUST 10th  17-00 (JST) to AUGUST 12th  17-00 (JST) Please kindly place orders on12th of August. after 17-00 JST Website will resume work from Friday evening (Japanese Standard Time) Sorry for the inconvenience. Sincerely yours JHC
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Reviews

John

Great product, original Japanese Lactis EL027826792JP
more ▶

Reviews

Mike

Good effect. I shall order again. Original made-in-japan package as promised EG401137451JP
more ▶

Reviews

May

Real Japanese laennec. Thank you! I shall order again. EJ377189782JP
more ▶

Reviews

Bob

Great effect! Got my hair back in 3 months. EG401137588JP
more ▶

Reviews

Nike

Lost 3 kilos since started to drink it last month. Great for fitness EG299855913JP
more ▶

Reviews

Any

Bought it for my son. Good effect and great service. EG299855961JP
more ▶

Reviews

Nya

Original touchi, fast delivery and good price. Thank you. EG401137156JP
more ▶

Reviews

Sam

Good medicine. Think it really helps me to fight cancer. EL025661542JP
more ▶

Reviews

John

3 times cheaper than in our country! And great effect for knees EJ365886698JP
more ▶

Reviews

Mike

Great thing to support diet. Lost 4 kilos for 6 weeks. Shall order more EJ365886675JP
more ▶