Pirenoxine ophthalmic suspension 0.005% for cataract (Kary Uni, Catalin)

General information on Japanese Pirenoxine ophthalmic suspension 0.005% for cataract (Kary Uni, Catalin)

Package details: 10 bottles * 5 ml

Manufacturer: Santen Pharmaceutical Co.,Ltd., Japan

Active ingredient: pirenoxine (chemical formula C16H8N2O5)

Medical effect: Pirenoxine ophthalmic suspension is effective for the treatment of early senile cataract.

Contraindications and precautions: do not use for pregnant and breastfeeding women. Do not use for patients with contact lenses.

As this medicine may cause staining your clothes, if you happen to contact the clothes with the medicine by accident, wash the stain with water as quickly as possible.

If an allergic reaction occurs, stop using the medicine and consult with your doctor. If you’re taking any other medication, please consult with your doctor before use.

Dosage and administration

• Apply 1-2 drops at a time, 3-5 times a day, as following:
• Before applying, wash your hands thoroughly with soap and running water.
• Shake the bottle well and open the cap.
• Pull down your lower eyelid lightly and apply the medicine.
• Be careful not touch your eyelid, eyelashes or eye with the dropper tip.
• After applying, keep your eyes closed without blinking for a while (1-5 minutes).
• Wipe off any excess liquid.

How effective is Pirenoxine ophthalmic suspension 0.005% from Japan for cataract (Kary Uni, Catalin)?

Pirenoxine is a pyridophenoxazine compound resembling xanthommatin. It works by competitively inhibiting quinone compound binding to water-soluble protein of the lens. By this, Pirenoxine ophthalmic solution prevents the lens protein degeneration.

Who should use Pirenoxine ophthalmic suspension 0.005% from Japan?

Pirenoxine ophthalmic suspension is effective for the treatment of early senile cataract. Studies showed that pirenoxine effectively reduces selenite and calcium ions associated with lens cataract formation and improves lens turbidity (Liao Jiahn-Haur, Chen Chien-Sheng et al. “Ditopic Complexation of Selenite Anions or Calcium Cations by Pirenoxine: An Implication for Anti-Cataractogenesis”. Inorganic chemistry, 2011, 50(1):365-77).