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New Year Holidays 2024 / 2025
03/12/2024
Please pay attention that due to local holidays in Japan (End of Year holidays – Dec 27th to Jan 5th) we shall operate as follows:
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LYFNUA Tablets 45 mg for refractory chronic cough (gefapixant)
Product Code :
Availability : 6
USD 425.00
Are LYFNUA Tablets 45 mg effective for refractory chronic cough (gefapixant)?
LYFNUA tablets offer a novel approach to managing refractory chronic cough, providing relief where other treatments may fall short. These tablets operate by targeting the underlying mechanism of chronic cough, effectively suppressing persistent coughing episodes. At the core of their mechanism lies the selective inhibition of nerve switches known as P2X3 receptors within the airways, crucial elements in the activation of sensory neurons responsible for triggering the cough reflex.
The active ingredient in LYFNUA tablets, gefapixant, stands out as a pioneering solution in chronic cough treatment. As a first-in-class, non-narcotic, selective antagonist of the P2X3 receptor, gefapixant demonstrates remarkable efficacy in alleviating chronic cough symptoms. Multiple studies and clinical trials have underscored the effectiveness of this active compound. For instance, in the article titled "Update on the clinical development of gefapixant, a P2X3 receptor antagonist for the treatment of refractory chronic cough," researchers affirm the capability of gefapixant to address both refractory chronic cough and unexplained chronic cough.
The benefits of LYFNUA tablets extend beyond mere symptom relief. By specifically targeting the P2X3 receptors, these tablets offer a tailored approach to chronic cough management, addressing the root cause of the condition. This targeted action not only mitigates coughing episodes but also helps improve overall quality of life for individuals grappling with refractory chronic cough.
In the realm of chronic cough treatment, LYFNUA tablets emerge as a promising option for those seeking effective relief. Their unique mechanism of action, powered by the potent antagonist gefapixant, sets them apart as a front-line solution for refractory chronic cough. With their proven efficacy and targeted approach, LYFNUA tablets represent a significant advancement in the management of chronic cough, offering hope and relief to patients where conventional treatments have fallen short.
Package details: 100 tablets
Dosage and administration: For adults, take one tablet (45 mg of gefapixant) twice daily. Patients with severe kidney disease not undergoing dialysis should take one tablet once daily.
Active components: gefapixant citrate
Therapeutic effect: treatment of refractory chronic cough
Contraindications and precautions: You may encounter taste impairments such as bitterness, metallic taste, saltiness, or difficulty sensing taste or enjoying food. If you have impaired kidney function, regular renal function tests may be necessary. Do not use for pregnant or breastfeeding women. Patients with kidney disease or dialytic treatment should consult with their doctor before use. Do not expose to sunlight or heat. If allergic symptoms occur, discontinue use.
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New Year Holidays 2024 / 2025
03/12/2024
Please pay attention that due to local holidays in Japan (End of Year holidays – Dec 27th to Jan 5th) we shall operate as follows:
ORDER ACCEPTANCE
We stop accepting orders during holidays from Dec 26th to Jan 3rd. Website will not allow orders, please order on Jan 3rd, evening (Japanese time)
No suppliers will operate this week so changes in shipping time / price / product availability are possible. Product may become unavailable as well.
Please pay attention: orders paid after Dec 15th may be shipped after Jan 6th because Japan Post and courier services will not operate during Holidays. If you pay before we are 99% likely to ship before holidays. If you pay after make sure you can wait as delays are possible due to end of year holidays. Some suppliers stop working before Dec 26th, please pay attention!
SUPPORT TEAM and PAYMENT CONFIRMATIONS
Will not work on Dec 31st , Jan 1st Jan 2nd - No email of any urgency will be replied. Thank you for understanding. Do not send sseveral emails during this period.
We shall resume support work on Jan 3rd, but we may need time to reply.
We shall continue to work as usual starting Jan 6th.
Pay attention that payments may be affected by your local holidays in your country / country of payment systems (during Christmas holidays and New Year holidays).
SHIPIPNG - DELAYS till January 10th.
We stop shipping all orders from Dec 28th to Jan 6th. Japan Post and courtier services will not work during this period so there are possible delays for some orders (mainly injections and some tablets) paid after Dec 15th
We shall resume normal work from Monday 6th.