Limaprost Alfadex tablets 5 mcg for numbness and pain in limbs (lumbar spinal stenosis, thromboangiitis obliterans, Nichi-Iko, Opalmon, Prorenal)

General information on Japanese Limaprost Alfadex tablets 5 mcg for numbness and pain in limbs (lumbar spinal stenosis, thromboangiitis obliterans, Nichi-Iko, Opalmon, Prorenal)

Package details: 100 tablets in the bottle

Manufacturer: Nichi-Iko Pharmaceutical Co., Ltd., Japan / SAWAI etc

Active ingredient: limaprost alfadex (chemical formula C22H36O5)

Medical effect: Limaprost Alfadex tablets are effective for the treatment of the following diseases and conditions:

• leg numbness or pain caused by lumbar spinal stenosis,
• walking ability impaired by lumbar spinal stenosis,
• ulcer, pain and coldness caused by thromboangiitis obliterans,
• leg pain or numbness and walking ability caused by acquired lumber spinal stenosis for patients who are proved normal in SLR test and have bilateral intermittent claudication.

Contraindications and precautions: do not use for pregnant and breastfeeding women. If an allergic reaction occurs, stop taking the medicine and consult with your doctor. If you’re taking any other medication, please consult with your doctor before use.

Dosage and administration of Limaprost Alfadex tablets 5 mcg Nichiiko from Japan for numbness and pain in limbs (lumbar spinal stenosis, thromboangiitis obliterans, Nichi-Iko)

For thromboangiitis obliterans: for adults, take 2 tablets (10 mcg of active ingredient) at a time, 3 times a day.

For acquired lumbar spinal stenosis: for adults, take 1 tablet (5 mcg of active ingredient) at a time, 3 times a day.

How effective are Limaprost Alfadex 5 mcg tablets from Japan for numbness and pain in limbs (lumbar spinal stenosis, thromboangiitis obliterans, Nichi-Iko)?

Limaprost Alfadex is an oral prostaglandin E1 analog. It acts on vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Limaprost Alfadex tablets improve peripheral circulatory failure with a vasodilator action and an antithrombotic effect, improve poor blood flow in the nerve tissue in cervical spondylosis and normalize nerve function. As the result, this medicine effectively helps to relieve such symptoms as numbness, pain or coldness in limbs (both legs and arms) and to significantly improve walking ability.

Who should take Limaprost Alfadex tablets 5 mcg from Japan?

Limaprost Alfadex tablets are recommended for patients with thromboangiitis obliterans and acquired lumbar spinal canal stenosis (in patients with bilateral intermittent claudication showing normal SLR test result). Also, Japanese researches point out this medicine’s effectiveness for the treatment of lumbar spinal stenosis patients with concurrent osteoporosis (especially elderly patients) and patients with cervical spondylotic radiculopathy (T. Kinchiku, Y. Imajo et al. “Comparisons on Efficacy of Elcatonin and Limaprost Alfadex in Patients with Lumbar Spinal Stenosis and Concurrent Osteoporosis: A Preliminary Study Using a Crossover Design”. Asian Spine Journal, 2014; 8(4): 469-475).