Glucoline injections for hepatic dysfunction (monoammonium glycyrrhizinate, L-cysteine, glycine)

General information on Japanese Glucoline injections for hepatic dysfunction (monoammonium glycyrrhizinate, L-cysteine, glycine)

Package details: 50 polyampoules * 20 ml

Manufacturer: Fuso Pharmaceutical Industries, Ltd., Japan

Active ingredients: monoammonium glycyrrhizinate (chemical formula C42H62O16·NH3), L-cysteine ​​hydrochloride hydrate (chemical formula C3H10ClNO3S), glycine (chemical formula C2H5NO2)

Medical effect: Glucoline injections are effective for improving hepatic dysfunction in the following disease and conditions:

• pediatric strophulus,
• eczema or dermatitis,
• urticaria,
• pruritus dermatitis,
• stomatitis,
• phlycten,
• drug eruption or toxic eruption,
• chronic liver disease.

Contraindications and precautions: do not use for pregnant or breastfeeding women. Do not use for patients with aldosteronism, myopathy, or hypokalemia.

If an allergic reaction occurs, stop using the medicine and consult with your doctor. If you’re taking any other medication or receiving any other treatment, you have to consult with your doctor before use.

Dosage and administration

For adults: take 5-20 ml intravenously once daily. The doctor in charge may adjust the dosage according to the patient's age and symptoms.

For chronic liver disease, take 40-60 ml via intravenous injection or intravenous infusion once a day. The doctor in charge may adjust the dosage according to the patient's age and symptoms. However, the maximum daily dose of 100 ml should not be exceeded.

How effective are Glucoline injections from Japan for hepatic dysfunction (monoammonium glycyrrhizinate, L-cysteine, glycine)?

Glucoline injections contain monoammonium glycyrrhizinate, L-cysteine ​​hydrochloride hydrate and glycine. Glycine provides protective effect on the liver, elevating the level of fatty acid transport proteins. Studies showed that combination of monoammonium glycyrrhizinate and cysteine ​​hydrochloride improves oxidative stress and inflammation of liver, increasing survival percentage, decreasing ALT and AST level and improving hepatic pathology (Shifeng Chua, Ziquan Niu et al. “Combination of monoammonium glycyrrhizinate and cysteine hydrochloride ameliorated lipopolysaccharide/galactosamine-induced acute liver injury through Nrf2/ARE pathway”. European Journal of Pharmacology, 2020, Volume 882, 173258).

Who should use Glucoline injections from Japan?

Glucoline injections work by suppressing inflammation and allergic response of the body, by this, improving the condition of the liver. They are effective for the treatment of hepatic dysfunction in patients with pediatric strophulus, eczema or dermatitis, urticaria, pruritus dermatitis, stomatitis, phlycten, drug eruption or toxic eruption and chronic liver disease.