Eybelis ophthalmic solution 0.02% for glaucoma and ocular hypertension (omidenepag isopropyl)
Product Code :
Availability : 15
General information on Japanese Eybelis ophthalmic solution 0.02% for glaucoma and ocular hypertension (omidenepag isopropyl)
Package details: 2.5 ml * 5 bottles
Manufacturer: Santen Pharmaceutical Co., Ltd., Japan
Active ingredients: omidenepag isopropyl (chemical formula C26H28N6O4S)
Medical effect: Eybelis eye drops are effective for the treatment of ocular hypertension and glaucoma.
Contraindications and precautions: do not use for the following categories of patients:
- Pregnant or breastfeeding women,
- Patients wearing contact lenses,
- Patients with aphakic or pseudophakic eyes,
- Patients with ocular inflammatory disease such as iritis or uveitis.
If an allergic reaction occurs, stop using the medicine and consult with your doctor. If you’re taking any other medication or receiving any other treatment, you have to consult with your doctor before use.
As this medicine may cause temporarily blurred vision or sensitiveness to bright light after applying, patient should not operate dangerous machinery or drive a car until these symptoms recover. If bloodshot eye symptom appears, consult with your doctor.
As 2.5 ml of ophthalmic solution is packed into a 5 ml bottle for easier extraction, it may seem that the bottle is not full, that’s not true.
Store the bottles in the refrigerator (2-8 degrees Celsius) and in the shading bag, as this medicine is sensitive to light. When the bottle is opened, it should be stored in the shading bag at a room temperature or in the refrigerator, but the storage period should not exceed 1 month.
Dosage and administration
Wash your hands thoroughly with soap and water. Pull down the lower eyelid gently and apply 1 drop at a time, once a day. Close the eyes and wait without blinking for 1-5 minutes. After that, gently press the inner corners of the eyes and wipe off any excess liquid with clean gauze or a tissue.
Be careful not touch the eyelid, eyelashes, or eye with the tip of the bottle. If patient needs to apply other eye drops at the same time, wait more than 5 minutes before the applying. If patient wears soft contact lenses, the lenses should be taken off before applying and wear them again in at least 5-10 minutes after applying.
How effective is Eybelis ophthalmic solution 0.02% from Japan for glaucoma and ocular hypertension (omidenepag isopropyl)?
Eybelis ophthalmic solution contains omidenepag isopropyl, a non-prostanoid selective EP2 receptor agonist. It works by stimulating prostaglandin EP2 receptor, promoting aqueous humor outflow via trabecular outflow route and uveoscleral outflow route and decreasing ocular pressure.
Who should use Eybelis ophthalmic solution 0.02% from Japan?
For patients with glaucoma, decreasing intraocular pressure is a main treatment allowing to prevent glaucomatous visual field loss. Japanese scientists proved that omidenepag shows better results with intraocular pressure control and fewer side effects than other prostanoid receptor agonists (T. Kirihara, T. Taniguchi et al. “Pharmacologic Characterization of Omidenepag Isopropyl, a Novel Selective EP2 Receptor Agonist, as an Ocular Hypotensive Agent”. Investigative Ophthalmology & Visual Science January 2018, Vol.59, 145-153). Eybelis ophthalmic solution provides a significant ocular hypotensive effect in both ocular normotensive and hypertensive models, providing an effective treatment of glaucoma.