Coralan tablets 5 mg for chronic heart failure (ivabradine hydrochloride)

Are Coralan tablets 5 mg effective for chronic heart failure (ivabradine hydrochloride)?

Managing chronic heart failure treatment effectively requires innovative solutions that improve heart function while minimizing side effects. Coralan tablets, formulated with ivabradine hydrochloride, provide a targeted approach to reducing heart rate without compromising cardiac contractility. As a result, they play a crucial role in enhancing cardiovascular efficiency and improving patient outcomes for individuals suffering from chronic heart failure and angina treatment.

 

Coralan’s active ingredient, ivabradine hydrochloride, is a hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker. It works by selectively inhibiting the If current in the sinoatrial node, effectively slowing heart rate without the negative inotropic effects associated with beta-blockers and calcium channel blockers. This mechanism reduces myocardial oxygen demand, allowing the heart to function more efficiently. Additionally, it improves blood flow to the myocardium, enhancing oxygen supply to heart tissues. Unlike traditional angina tablets, Coralan provides a selective effect on heart rate without affecting blood pressure or contractility, making it a well-tolerated choice for patients with heart conditions.

 

Clinical Effectiveness and Safety

Numerous studies have demonstrated the efficacy and safety of ivabradine tablets in patients with chronic heart failure treatment. A Japanese study, titled “The efficacy and safety of ivabradine hydrochloride in hemodialysis patients with chronic heart failure,” highlighted significant benefits:

 

Benefits of Coralan Tablets for Angina and Heart Failure Patients

 

Patients suffering from chronic heart failure and angina treatment can benefit from Coralan in multiple ways:

 

For individuals seeking an effective chronic heart failure treatment, Coralan tablets provide a clinically proven solution that reduces heart rate while preserving cardiac function. With ivabradine tablets, patients experience better heart health, reduced angina symptoms, and improved overall well-being. Consult your healthcare provider to determine if Coralan is the right angina treatment for your condition.

 

Package details: 100 tablets

Dosage and administration: adults should start with taking 0.5 tablets (2.5 mg of ivabradine) at a time 2 times a day after meals. When increasing or decreasing the dosage, it should be done gradually, with an interval of at least 2 weeks, according to the heart rate at rest and tolerability. A standard dosage is either 0.5 tablets. 1 tablet or 1.5 tablets (2.5, 5 or 7.5 mg of active ingredient), twice a day after meals. Your doctor may adjust the dosage according to your conditions. Please note that this medicine contains 5 mg of ivabradine in a tablet.

Active components: ivabradine hydrochloride

Therapeutic effect: improving chronic heart failure with sinus rhythm and heart rate at rest of over 75 beats per minute at the start of treatment course

Contraindications and precautions: Store in a dry cool place, out of reach of children. Do not use for pregnant, possibly pregnant or breastfeeding women. Do not use for patients with unstable/acute heart failure, cardiogenic shock, hypotension, sick sinus syndrome, sinoatrial block/third-degree atrioventricular block (excluding patients with a pacemaker), patients with liver dysfunction (Child-Pugh C), patients with tachycardiac arrhythmia (ventricular or supraventricular), first-degree and second-degree atrioventricular block, ventricular conduction disorder (bundle branch block) or ventricular dyssynchrony. 

If you accidentally exceed your prescribed dose, you may experience bradycardia, which can cause symptoms such as dizziness, lightheadedness when standing up, shortness of breath, a slow pulse, irregular heartbeats, or fainting. If multiple symptoms occur simultaneously, stop taking the medication and consult with health care professionals immediately. Female patients who may become pregnant should avoid pregnancy while taking this medication and for a specified period after completing the treatment. Use with caution when operating hazardous machinery, including driving, as this medication may cause symptoms such as sudden flashes of light in the dark, blurry vision, dizziness, and lightheadedness. If you experience any of these symptoms, strictly avoid driving or operating dangerous machinery. Avoid taking this medication with St. John’s Wort or grapefruit juice, as these substances may alter its effectiveness by either reducing or enhancing its medicinal effects.

Do not expose to sunlight or heat. If allergic symptoms occur, discontinue use.