Azanin (azathioprine, imuran) tablets for Crohn's disease 50 mg from Japan

General information on Azanin (azathioprine, imuran) tablets for Crohn's disease 50 mg from Japan

Package details: 100 tablets

Manufacturer: Mitsubishi Tanabe Pharma, Japan

Active ingredient: azathioprine (chemical formula C9H7N7O2S).

Medical effect: azathioprine slows the development and growth of immunocompetent cells, acting as an immunosuppressant. Thus, it reduces the inflammatory process and supports the action of steroids in Crohn's disease.

Dosage and administration:

For adults, the dosage is 50-100 mg of active ingredient per day, For children 1-2 mg of the active substance per 1 kg of weight per day.

Contraindications, precautions:

Do not use for pregnant and lactating women. In patients with renal and hepatic insufficiency, the medication should be used with caution, under the supervision of a physician. When used together with allopurinol, oxypurinol or thiopurinol, the dosage should be reduced by 4 times.

How effective are Azanin (azathioprine, imuran) tablets for Crohn's disease 50 mg from Japan?

The Japanese tablets Azanin (azathioprine, imuran) for Crohn's disease 50 mg are effective to achieve stable remission in patients with Crohn's disease. The preparation can be used together with steroids and salicylates to increase their effect. Researchers note that the effect of azathioprine is stable but slow (N. Chande, P. H. Patton et al. Azathioprine or 6-mercaptopurine for maintenance of remission in Crohn's disease. The Cochrane database of systematic reviews. 2015 Oct 30; (10)). It is especially effective to use Azanin after the end of the steroid course to maintain stable remission (maintaining the course from 3 months to 2-3 years).

Who can use tablets for Crohn's disease Azanin (azathioprine, imuran) 50 mg from Japan?

Japanese tablets for Crohn’s disease Azanin (azathioprine, imuran) 50 mg from Japan are suitable for patients of all ages, including children and the elderly people. Azanin can be used during the course of treatment with steroids in the active phase of the disease and after the end of the course of steroids to consolidate the effect. This medication is especially recommended for patients with intolerance to mesalazine or sulfasalazine and to patients who need a second course of steroids. It is also possible to use azathioprine together with salicylates, however, the dosage should be adjusted by the consulting doctor.