Aricept tablets 10 mg for dementia.
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General information on Japanese Aricept tablets 10 mg for dementia
Package details: 100 tablets
Manufacturer: Eisai Co., Ltd., Japan
Active ingredient: donepezil hydrochloride (chemical formula C24H30ClNO3)
Medical effect: Aricept tablets are effective for slowing progression of symptoms of dementia associated with Alzheimer's disease and Lewy body dementia.
Contraindications and precautions: Aricept tablets cannot be used for the following categories of patients:
- patients with heart diseases such as sick sinus syndrome, sinoatrial block or atrioventricular block,
- patients with Parkinson's disease/syndrome
- patients with history of gastric/duodenal ulcer,
- pregnant or breastfeeding women.
Dosage and administration of Japanese tablets Aricept 10 mg for dementia
For Alzheimer's disease: take 3 mg as the active ingredient 1 time a day for the first 1-2 weeks. Subsequently, increase the dose to 5 mg 1 time a day. After taking 5 mg dosage for 4 weeks, according to the symptoms the consulting doctor may increase the dosage to 10 mg 1 time a day.
For Lewy body dementia: take 3 mg as the active ingredient 1 time a day for the first 1-2 weeks. Subsequently, increase the dose to 5 mg 1 time a day. After taking 5 mg dosage for 4 weeks, according to the symptoms the consulting doctor may increase the dosage to 10 mg 1 time a day. But the dosage may be decreased back to 5 mg 1 time a day if needed.
Please note that 1 tablet contains 10 mg of the active ingredient. If the dosage is increased to 10 mg at a time once a day, pay attention to gastrointestinal adverse reactions. Do not let the patient drive the car or operate the machinery while taking this medicine.
How effective are Aricept tablets 10 mg from Japan for dementia?
Aricept tablets contain donepezil hydrochloride, a substance that inhibits an enzyme hydrolyzing the neurotransmitter acetylcholine in the brain. By increasing levels of available acetylcholine, donepezil partly compensates the loss of functioning cholinergic brain cells. In this way, Aricept tablets delay progression of the symptoms of dementia such as memory loss, repeated conversations and actions or impaired judgment (J. Knowles. Donepezil in Alzheimer’s disease: an evidence-based review of its impact on clinical and economic outcomes. Core Evidence, 2006; 1(3): 195–219).
Who should use Aricept tablets 10 mg for dementia?
Aricept tablets are used for treatment of cognitive decline in patients with mild to moderate Alzheimer’s disease and improved cognitive function in in patients with dementia with Lewy bodies. This medicine stabilizes the cognitive and functional symptoms and slows the progress of the disease. While donepezil is unable to cure the dementia completely, it can delay deterioration in behavior and mood and significantly lessen caregiver burden.