Acofide tablets 100 mg for functional dyspepsia

General information on Japanese Acofide tablets 100 mg from Japan for functional dyspepsia    

Package details: 100 tablets

Manufacturer: Zeria Pharmaceutical Co., Ltd., Japan

Active ingredient: acotiamide hydrochloride hydrate (chemical formula C21H30N4O5S)

Medical effect: Acofide tablets are effective for the treatment of functional dyspepsia and its simptoms, including:

• postprandial fullness,
• upper abdominal bloating,
• early satiety,
• nausea.

Contraindications and precautions: do not use in pregnant or breastfeeding women. If an allergic reaction occurs, stop using the medication and consult with your doctor. If you’re taking any other medication, please consult with your doctor before use.

Dosage and administration of Japanese Acofide tablets 100 mg for functional dyspepsia

Take 1 tablet (100mg of the active ingredient) 3 times a day before meals. Never take 2 tablets at once.

How effective are Acofide tablets 100 mg from Japan for functional dyspepsia?

Acofide tablets improve gastrointestinal motility and promote excretion of stomach contents by inhibiting acetylcholinesterase activities. But the efficacy of this medication tends to decrease for up to 40% when being taken after meal or on empty stomach. That’s why it should be taken strictly before the meals.

Who should use Acofide tablets 100 mg from Japan for functional dyspepsia?

Acofide tablets are effective against postprandial fullness, upper abdominal bloating, and early satiation caused by functional dyspepsia. Studies show that Acofide tablets are especially effective on meal-related symptoms of functional dyspepsia, with post hoc analysis showing great improvement rate in overall treatment efficacy in patients taking the optimal dosage of acotiamide hydrochloride (K. Matsueda, M. Hongo et al. Clinical trial: dose-dependent therapeutic efficacy of acotiamide hydrochloride (Z-338) in patients withfunctional dyspepsia – 100 mg t.i.d. is an optimal dosage. Neurogastroenterology & Motility, 2010, June, 22 (6): 618–e173).