Aciclovir IV drip infusion 250 mg (antiviral, virus, herpes, varicella)

General information on Japanese Aciclovir IV drip infusion 250 mg (antiviral, virus, herpes, varicella)

Package details: 5 vials * 10 ml (250 mg of aciclovir in each vial)

Manufacturer: Nichi-Iko Pharmaceutical Co., Ltd, Japan

Active ingredient: aciclovir (chemical formula C8H11N5O3)

Medical effect: Aciclovir IV drip infusion is effective for the treatment of infection caused by

• herpes simplex,
• varicella,
• herpes zoster virus,
• neonatal herpes simplex virus.

Contraindications and precautions: do not use for pregnant and breastfeeding women.

Patient should take a larger amount of water than usual, unless their doctor in charge instructed fluid restriction.

As this medicine may cause lack of consciousness, especially in patients with renal dysfunction, patient should avoid working at heights, driving a car or operating dangerous mechanisms while taking this medicine.

If an allergic reaction occurs, stop taking the medicine and consult with your doctor. If you’re taking any other medication, please consult with your doctor before use.

Dosage and administration

For adults, children and newborns: inject by intravenous infusion 3 times a day.

The average course of treatment for adults and children is 7 days, and for neonatal HSV infection is 10 days. The consulting doctor may extend the treatment according to patient's symptoms.

How effective is Aciclovir IV drip infusion 250 mg from Japan (antiviral, virus, herpes, varicella)?

Aciclovir is a synthetic purine nucleoside analogue that converts in the human body into aciclovir monophosphate and aciclovir triphosphate. Aciclovir monophosphate incorporates into the viral DNA, resulting in chain termination, and aciclovir triphosphate competitively inhibits and inactivates the viral DNA polymerase. As the result, Aciclovir IV drip infusion effectively suppresses the growth of viruses.

Who should use Aciclovir IV drip infusion 250 mg from Japan?

Aciclovir IV drip infusion is effective for the treatment of viral infections caused by herpes simplex, varicella, herpes zoster virus and neonatal herpes simplex virus. As this medicine is is extremely selective and low in cytotoxicity, it can be used for newborn babies, children and adults. Studies showed that even the high dose of aciclovir is relatively safe for the newborns, as the adverse effects are not severe and, actually, are likely related to the underlying infection rather than due to acyclovir exposure (J.E. Ericson, M. Gostelow et al. “Safety of High-Dose Acyclovir in Infants with Suspected and Confirmed Neonatal Herpes Simplex Virus Infections” // The Pediatric Infectious Disease Journal, 2017, 36(4): 369–373).