Primidone tablets Nichi-iko 250 mg for epilepsy, seizures and tremor (Lepsiral, Mysoline, Resimatil)
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General information on Japanese Primidone tablets Nichi-iko 250 mg for epilepsy, seizures and tremor (Lepsiral, Mysoline, Resimatil)
Package details: 100 tablets
Manufacturer: Nichiiko Co., Ltd., Japan
Active ingredient: primidone (chemical formula C12H14N2O2)
Medical effect: Primidone tablets are effective for the treatment the following diseases and conditions:
- convulsive seizures (generalized tonic-clonic seizures, grand mal),
- psychomotor seizures (complex partial seizures),
- focal seizures (partial seizures, localized seizures),
- minor motor seizures,
- essential tremor.
Contraindications and precautions: do not use in pregnant and breastfeeding women. Do not use in patients with acute intermittent porphyria.
If an allergic reaction occurs, stop taking the medicine and consult with your doctor. If you’re taking any other medication, please consult with your doctor before use.
As this medicine may cause sleepiness and lack of attention, concentration or reflex movement, patients should avoid operating in potentially hazardous activities such as driving a car. Avoid drinking alcohol while taking this medication.
Dosage and administration of Primidone tablets Nichi-iko 250 mg from Japan for epilepsy, seizures and tremor (Lepsiral, Mysoline, Resimatil)
For adults: start with taking 1 tablet before going to bed for the first 3 days. Then, the dosage will be increased by 1 tablet every 3 days up to daily dose of 6 tablets. The standard daily dose should be divided into 2-3 doses a day. The consulting doctor may adjust the dosage according to age and symptoms. However, the maximum daily dosage should not exceed 8 tablets (2,000 mg of active ingredient) a day.
For children: start with taking 0.5 tablet (125 mg) before going to bed for the first 3 days. Then, the dosage should be increased by 0.5 tablet every 3-4 days up to the standard dose. Standard daily dose depends on age:
- for children under 2 years old: 1-2 tablets,
- for 3 to 5 years old: 2-3 tablets,
- for 6 to 15 years old: 3-4 tablets.
The standard daily dose should be divided into 2-3 times a day. The consulting doctor may adjust the dosage, according to age, weight and symptoms.
How effective are Primidone tablets Nichi-iko 250 mg from Japan for epilepsy, seizures and tremor (Lepsiral, Mysoline, Resimatil)?
Primidone is a barbiturate, particularly, a congener of phenobarbital with the carbonyl oxygen of the urea moiety being replaced by two hydrogen atoms. It acts on central nervous system as an anticonvulsant, effectively treating seizures and tremor.
Who should take Primidone tablets Nichi-iko 250 mg from Japan?
Primidone tablets can be used for both adults and children. This medicine can be used for the initial treatment of epilepsy and essential tremor. Primidone as a wells-studied agent, it proved its effectiveness for convulsive, psychomotor, focal, and minor motor seizures and essential tremor (E. A. Rodin, C. S. Rim et al. A comparison of the effectiveness of primidone versus carbamazepine in epileptic outpatients. The journal of nervous and mental disease. 1976, July, 163(1): 41-6).