Pentasa tablets for Crohn's disease 500 mg from Japan

General information on Pentasa tablets for Crohn's disease 500 mg from Japan

Package details: 100 tablets

Manufacturer: KYORIN Pharmaceutical Co., Ltd., Japan

Active ingredient: mesalazine 500 mg (chemical formula C7H7NO3).

Medical effect: mesalazine is effective in mild, moderate and moderately severe form of Crohn's disease. It has anti-inflammatory activity, because it works as an inhibitor of the prostaglandin synthesis. By blocking the synthesis of leukotrienes, this component also contributes to the healing of damaged sections of the intestine, reduces pain, relieves intestinal bleeding.

Dosage and administration:

In adults, take 1-2 tablets 3 times a day. In children, take the tablets 3 times a day at a rate of 40-60 mg of active substance per 1 kg of weight per day. Dosage can be adjusted by the consulting doctor.

Contraindications, precautions:

In pregnant women, the risks and the benefits should be discussed with the consulting doctor before use. While using the medication, the breastfeeding should not be performed. Mesalazine is also contraindicated in the following individuals:

• patients with hypersensitivity to salicylates,
• patients with impaired liver and kidney function,
• patients with gastric ulcer,
• patients with duodenal ulcer.

How effective are Pentasa tablets for Crohn's disease 500 mg from Japan?

Japanese Pentasa tablets from Crohn's disease 500 mg provide a high frequency of remission in patients with Crohn's disease. Mesalazine relieves irritation of the intestinal mucosa and heals intestinal bleeding, as it reduces the number of immune and mast cells in the intestinal mucosa. In older patients with mild Crohn's disease and the absence of pronounced changes in the mucous membrane according to the results of endoscopy, treatment with Pentasa tablets alone for at least 46 months is sufficient. In addition, mesalazine increases the effectiveness of other drugs in Crohn's disease, such as azathioprine (C. Prantera. The Role of Mesalamine in Crohn's Disease. In book: ADVANCED THERAPY IN INFLAMMATORY BOWEL DISEASE, 3RD EDITION VOL 2, Edition: 3RD Edition. 2010. Pp. 643-649). Pentasa tablets from Japan also inhibit bacterial growth in the intestines.

Who should use Pentasa tablets 500 mg from Japan?

Pentasa tablets from Crohn's disease 500 mg from Japan are suitable for patients with mild, moderate and moderately severe form of Crohn's disease who do not need surgical intervention. They relieve pain, accelerate the healing of the mucous membrane, relieve intestinal bleeding. With a mild form of Crohn's disease, treatment with Pentasa tablets only is sufficient, with more pronounced changes in the intestinal mucosa, Pentasa tablets can be taken together with immunosuppressive agents.