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John

Great product, original Japanese Lactis EL027826792JP
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Mike

Good effect. I shall order again. Original made-in-japan package as promised EG401137451JP
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May

Real Japanese laennec. Thank you! I shall order again. EJ377189782JP
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Bob

Great effect! Got my hair back in 3 months. EG401137588JP
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Nike

Lost 3 kilos since started to drink it last month. Great for fitness EG299855913JP
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Any

Bought it for my son. Good effect and great service. EG299855961JP
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Nya

Original touchi, fast delivery and good price. Thank you. EG401137156JP
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Sam

Good medicine. Think it really helps me to fight cancer. EL025661542JP
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John

3 times cheaper than in our country! And great effect for knees EJ365886698JP
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Mike

Great thing to support diet. Lost 4 kilos for 6 weeks. Shall order more EJ365886675JP
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Progynon Depot: effects and application area.

Progynon Depot: effects and application area.

Is Progynon Depot effective?

The active substance of Estradiol Valerate is sold worldwide under several names and trademarks across the globe. In Japan, it is known as Progynon Depot. This drug is widely used not only in Japan, but throughout the world. The scope of its application is quite wide - the following recognized areas of use for Proginon Depot can be enlisted:

  • hormone therapy
  • with a low level of estrogen,
  • for the treatment of menopause symptoms,
  • as hormonal contraception,
  • for the treatment of prostate cancer (men).
  • in the treatment of breast cancer (women).

Progynon Depot is administered intramuscularly, by applying once a week or once every few weeks, depending on the prescription of physician. Clinics started to use Estradiol Valerate actively since 1954. Starting from this year Progynon has gained wide popularity in the United States, Canada, Europe, Japan and many other countries over the world.

Progynon Depot from Japan

Estradiol is a naturally synthesized form of estrogen, because it is considered a natural active component and compared to numerous analogues, it causes less harm, with sufficiently significant positive therapeutic effects.

Estradiol Valerate sold in Japan under brand name Progynon Depot is available in different countries in the form of injections and in the form of tablets. However, injections are incomparably more effective than pills. For example. 4 mg. of medicine, administered intramuscularly, produces medical effect equivalent to the use of 2 mg of tablet medicine taken during three weeks (Düsterberg B, Nishino Y (December 1982). "Pharmacokinetic and pharmacological features of estradiol valerate". Maturitas. 4 (4): 315–24 ). This is one of those cases where injections are several times more effective. After intramuscular injection, the maximum concentration of Progynon in blood is maintained for three days at the level of 390 picograms per milliliter. After 3 days it drops three times, and it continues to maintain this level for another 9-10 days (Climacteric in Perspective: Menopause, held at Lake Buena Vista, Florida, October 28 – November 2, 1984. Springer Science & Business Media (pp. 397, 399).

At this moment, Progynon Depot is one of the most effective methods applied for hormonal therapy, as well as for therapeutic methods mentioned at the beginning of this article. Pay attention to possible contraindications and precautions before using Estradiol Valerate. If necessary, consult with your physician.

You can also check the following related article about menopause treatment:

Clinical trials of Melsmon: effects and contraindications

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Shipping to USA, EU, Asia, Oceania and South America in October

Dear Customers! We ship to USA, to EU, to almost all countries by Japan Post OR Express Courier Service! Japan Post imposed restrictions on shipping to USA, EU and most of other coutnries. Situation changes every day. Please check this link for details on each country by Japan Post. https://www.post.japanpost.jp/int/information/overview_en.html We can ship to Most Countries. Please ask us on detail.  WE STILL CAN SHIP TO MOST COUNTRIES - SEE DETAILS BELOW OR CONTACT US IF YOU HAVE QUESTIONS!   USA: - EXPRESS SERVICE. We ship everything but vials. Delivery takes 6-10 days.  - SURFACE MAIL. We ship all other items (vials), takes 7-9 weeks or more, we offer tracking, Rate starts at 19-29 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail.   EU - EUROPE We ship as usual (with possible delays) to the countries below (Alphabetic order):  Austria, Belgium, Bulgaria, Croatia, Czech, Denmark, Estonia, France (Monaco), Germany, Hungary, Italy, Latvia, Lithuania, Luxembourg, Netherlands (Holland), Norway, Poland, Portugal, Serbia, Slovenia, Spain, Sweden,     For other coutnries in Europe (Romania, Greece, Ukraine etc): We ship using express service to all other countries in EU at the moment. We can ship by express method for tablets and flat supplements in total weight not exceeding 0,5 kg. We ship in 7-12 business days. Delivery takes 6-10 days. USE EXPRESS METHOD. We can ship using surface mail. This takes 4-6 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail.   ASIA - SINGAPORE, HONG KOG, KOREA, PHILIPPINES, TAIWAN, THAILAND, VIETNAM, MALAYSIA, PHILIPPINES. We ship as usual (with possible delays) to these countries   SHIPPING TO CHINA. We ship as usual by EMS or Surface mail.    SHIPPING TO INDIA. - WE STILL CAN SHIP TABLETS/CAPSULES. We can ship by express method for tablets and flat supplements in total weight not exceeding 0,5 kg. We ship in 7-12 business days. Delivery takes 8-14 days. USE EXPRESS METHOD. - WE SHIP BY SURFACE MAIL. This takes 4-6 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail.   OCEANIA - AUSTRALIA. NEW ZEALAND To Australia: - WE STILL CAN SHIP TABLETS/CAPSULES. We can ship by express method for tablets and flat supplements in total weight not exceeding 0,5 kg. We ship in 7-12 business days. Delivery takes 8-14 days. USE EXPRESS METHOD. - WE SHIP BY SURFACE MAIL. This takes 4-6 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail. TO NEW ZEALAND - WE SHIP AS USUAL    BRAZIL - WE STILL CAN SHIP TABLETS / CAPSULES / EYE DROPS. We can ship by express method for tablets and flat supplements in total weight not exceeding 0,5 kg. We ship in 7-12 business days. Delivery takes 8-14 days. USE EXPRESS METHOD. - WE SHIP BY SURFACE MAIL. This takes 4-6 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail.   CANADA We ship as usual with delays due to reduced number of flights.   RUSSIA, UKRAINE, KAZAKHSTAN. - TO RUSSIA  WE SHIP ONLY BY SURFACE MAIL. This takes 5-6 weeks or more, we offer tracking, Rate starts at 19 usd, free shipping for orders above 400 usd. If you can wait use this method. We can only ship vials and glass using surface mail. - TO UKRAINE WE SHIP BY COURIER MAIL OR BY SURFACE MAIL.  - WE CAN SHIP TO KAZAKHSTAN BY AIRMAIL WITH DELAYS. 
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Reviews

John

Great product, original Japanese Lactis EL027826792JP
more ▶

Reviews

Mike

Good effect. I shall order again. Original made-in-japan package as promised EG401137451JP
more ▶

Reviews

May

Real Japanese laennec. Thank you! I shall order again. EJ377189782JP
more ▶

Reviews

Bob

Great effect! Got my hair back in 3 months. EG401137588JP
more ▶

Reviews

Nike

Lost 3 kilos since started to drink it last month. Great for fitness EG299855913JP
more ▶

Reviews

Any

Bought it for my son. Good effect and great service. EG299855961JP
more ▶

Reviews

Nya

Original touchi, fast delivery and good price. Thank you. EG401137156JP
more ▶

Reviews

Sam

Good medicine. Think it really helps me to fight cancer. EL025661542JP
more ▶

Reviews

John

3 times cheaper than in our country! And great effect for knees EJ365886698JP
more ▶

Reviews

Mike

Great thing to support diet. Lost 4 kilos for 6 weeks. Shall order more EJ365886675JP
more ▶