How Eclar Plaster Works?
24/04/2024
How Eclar Plaster Works?
Eclar plaster, infused with deprodone propionate, a synthetic glucocorticoid corticosteroid, stands out as a versatile solution for addressing a spectrum of skin conditions, ranging from eczema and dermatitis to scars and keloids. This innovative plaster, formulated by Hisamitsu Pharmaceutical Co., Ltd. of Saga, Japan, has garnered attention since its launch in July 2001.
The effectiveness of Eclar plaster lies in its active ingredient, deprodone propionate. This synthetic glucocorticoid corticosteroid exerts its therapeutic effects by modulating the inflammatory response within the skin. By targeting various inflammatory mediators and pathways, Eclar plaster effectively mitigates symptoms such as itching and swelling, providing relief to individuals afflicted by a myriad of dermatological conditions.
Addressing Inflammation and Its Consequences
Eclar plaster operates by suppressing the activity of leukocytes and monocytes, key players in the inflammatory cascade. By doing so, it curtails the release of pro-inflammatory cytokines and chemokines, thereby dampening the inflammatory milieu within affected tissues. Additionally, Eclar plaster facilitates the reduction of plasma protease inhibitors, thereby promoting collagenase activity. This mechanism is pivotal in preventing the aberrant accumulation of collagen characteristic of keloids and hypertrophic scars.
Targeting Keloids and Hypertrophic Scars
One of the standout applications of Eclar plaster is in the management of keloids and hypertrophic scars. By virtue of its anti-inflammatory properties, Eclar plaster aids in curbing the excessive proliferation of fibroblasts and collagen deposition characteristic of these conditions. Continuous application of corticosteroid tapes or plasters postoperatively has been shown to significantly reduce the incidence of keloid formation following surgical procedures.
Patients utilizing Eclar plaster are advised to adhere to a regimen tailored to their individual needs.
- Continuous application of the plaster is recommended until the elevated mass of the keloid or hypertrophic scar becomes flat and soft, signifying a favorable response to treatment.
- The color of the scar cannot be used for measuring the effectiveness of the treatment. Once the scar is becoming flat and soft, the patient should cease the treatment even if the scar appears to be still bright red rather then pink. It will bleach gradually after finishing the treatment.
- Patients should exercise care in cutting the plaster to conform to the shape of the affected area, ensuring optimal coverage and efficacy.
Eclar plaster, with its potent formulation of deprodone propionate, represents a stalwart ally in the management of inflammatory skin conditions, scars, and keloids. Its mechanism of action, targeting key inflammatory pathways, underscores its efficacy in providing symptomatic relief and promoting tissue remodeling. With a track record of success and the endorsement of dermatological practitioners worldwide, Eclar plaster stands as a beacon of hope for individuals grappling with dermatological afflictions. You can purchase genuine Japanese Eclar plaster by Hisamitsu in our store.