Cetirizine hydrochloride tablets 5 mg for allergy (Zyrtec, antihistamine)
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General information on Japanese Cetirizine hydrochloride tablets 5 mg for allergy (Zyrtec, antihistamine)
Package details: 100 tablets
Manufacturer: Sawai Pharmaceutical Co., Ltd. / Nipro Pharma Corporation / Ohara Pharmaceutical Co., Ltd., Japan
Active ingredients: cetirizine hydrochloride (chemical formula C21H27Cl3N2O3)
Medical effect: Cetirizine hydrochloride tablets are effective for the treatment of following:
- allergic rhinitis is the main indication for use of Cetirizine hydrochloride tablets,
- eczema or dermatitis,
- prurigo and cutaneous pruritus.
Contraindications and precautions: do not use for pregnant or breastfeeding women. Do not use for patients with renal dysfunction.
As this medicine may provoke the sudden dizziness, the patient should avoid working at heights, operating dangerous machinery, or driving a car.
Refrain from taking alcohol while taking this medicine.
If an allergic reaction occurs, stop taking the medicine and consult with your doctor. If you’re taking any other medication or receiving any other treatment, you have to consult with your doctor before use.
Dosage and administration
For adults and children of 13 years old or more: take 2 tablets (10 mg of the active ingredient) at a time, once a day before bedtime. The doctor in charge may adjust the dosage according to the disease, age or symptoms. However, the maximum daily dose of 4 tablets (20 mg) should not be exceeded.
For children of 7-12 years old: take 1 tablet (5 mg) at a time, 2 times a day, after breakfast and before bedtime.
How effective are Cetirizine hydrochloride tablets 5 mg from Japan for allergy (Zyrtec, antihistamine)?
Cetirizine hydrochloride is a highly selective antagonist of the histamine H1 receptor and an anti-inflammatory drug. By suppressing the action of histamine and inflammatory response, it significantly improves the allergic symptoms. It provides no cardiotoxicity and does not undergo extensive metabolism. Due to that, Cetirizine hydrochloride tablets don’t interact with many medicines that inhibit or induce cytochrome enzymes and can be prescribed in combination with other drugs, like antibiotics.
Who should use Cetirizine hydrochloride tablets 5 mg from Japan?
Cetirizine hydrochloride tablets are effective for the treatment of allergic rhinitis, hives, eczema and dermatitis, prurigo and cutaneous pruritus. They can be used for both adults and children over 7 years old. Studies showed that cetirizine, unlike many other antihistamines, produces minimal sedation due to minimal crossing of the blood–brain barrier (A. Gupta, P. Chatelain et al. "Brain distribution of cetirizine enantiomers: comparison of three different tissue-to-plasma partition coefficients: K(p), K(p,u), and K(p,uu)". Drug Metabolism and Disposition, 2006, 34 (2): 318–23).