Azelnidipine tablets 8 mg for hypertension (Azusa, Azovas)

General information on Japanese Azelnidipine tablets Nichiiko 8 mg for hypertension (Azusa, Azovas)

Package details: 100 tablets

Manufacturer: Nichi-Iko Pharmaceutical Co., Ltd., Japan

Active ingredients: azelnidipine (chemical formula C33H34N4O6)

Medical effect: Azelnidipine tablets are effective for the treatment of hypertension.

Contraindications and precautions: do not use for pregnant, possibly pregnant or breastfeeding women.

If an allergic reaction occurs, stop taking the medicine and consult with your doctor. If you’re taking any other medication or receiving any other treatment, you have to consult with your doctor before use.

Avoid taking grapefruit juice while taking this medicine. As the decreased blood pressure may cause dizziness, be careful when driving a car, working at heights or operating in other potentially hazardous activities.

Dosage and administration of Azelnidipine tablets Nichiiko 8 mg from Japan for hypertension (Azusa, Azovas)

For adults, start with 1 tablet (8 mg) or less at a time, once a day after breakfast, as an initial dose. Then, if the effect is insufficient, the dosage may be increased up to 2 tablets (16 mg of the active ingredient) at a time, once a day after breakfast. The doctor in charge may adjust the dosage according to patient’s symptoms. However, the maximum daily dose of 2 tablets (16 mg) should not be exceeded.

How effective are Azelnidipine tablets Nichiiko 8 mg from Japan for hypertension (Azusa, Azovas)?

Azelnidipine is a dihydropyridine L and T calcium channel blocker. It works by blocking calcium inflow into cells and consequently dilating constricted vessels to decrease blood pressure.

Who should use Azelnidipine tablets Nichiiko 8 mg from Japan?

Azelnidipine tablets are effective for the treatment of essential hypertension. They have multiple benefits comparing to other anti-hypertension drugs:

• A gradual onset provides little increase in heart rate, so this medicine does not provoke tachycardia;
• A long-lasting hypotensive effect;
• Azelnidipine tablets are generally well tolerated and have very few side effects.

Studies proved that azelnidipine provides cardiovascular protective effects, like anti-oxidative action, decreasing heart rate, and improving systolic and diastolic function (B. Chen, Y. Zhang et al. “Clinical use of azelnidipine in the treatment of hypertension in Chinese patients”. Therapeutics and Clinical Risk Management, 2015, 11: 309-318).